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E-book

Title Neurochemistry of abused drugs / edited by Steven B. Karch

Published Boca Raton : CRC Press, [2008]
©2008
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Description 1 online resource (150 pages) : illustrations
polychrome rdacc http://rdaregistry.info/termList/RDAColourContent/1003
Contents The dopamine transporter and addiction / William M. Meil and John W. Boja -- Neurochemistry of nicotine dependence / Darlene H. Brunzell -- Neurochemical substrates of habitual tobacco smoking / Irina Esterlis, Suchitra Krishnan-Sarin, and Julie K. Staley -- Neurochemical and neurobehavioral consequences of methamphetamine abuse / Colin N. Haile -- Neurochemical adaptations and cocaine dependence / Kelly P. Cosgrove and Julie K. Staley -- Neuropsychiatric consequences of chronic cocaine abuse / Deborah C. Mash -- Neurobiology of 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") / Michael H. Baumann and Richard B. Rothman
Summary Beginning with a detailed look at individual drugs and their effects on the brain, "Neurochemistry of Abused Drugs" considers the changes in neurotransmitter levels and discusses the relationship of these changes to the nature and phenomenon of addiction. New studies highlight the addictive capacity of nicotine as well as introduce novel compounds that may aid in tobacco cessation. Chapters examine nicotine dependant neuroplasticity and the various neurochemical substrates that support and promote addiction including cholinergic, dopaminergic, and GABAergic adaptations.; The book also offers detailed information on the neurochemical and neurobehavioral consequences of MDMA, methamphetamine, and cocaine use. Recent discoveries on the neurotransmitter systems involved in each of these drugs reveal new therapeutic targets for alleviating addiction including ibogaine, and GABA and glutamate receptors. Extensively referenced and citing numerous up-to-date studies, this book provides unparalleled insight into the action and potential inhibition of drugs of abuse
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Drug abuse -- Pathophysiology.
Drugs of abuse -- Physiological effect.
Neurochemistry.
Neurotoxicology.
Brain -- drug effects.
Neurochemistry.
Neurotoxicity Syndromes -- etiology.
Street Drugs.
Substance-Related Disorders -- complications.
Substance-Related Disorders -- physiopathology.
Form Electronic book
ISBN 1281136697
1420054422 (electronic bk.)
9781281136695
9781420054422 (electronic bk.)
(hardcover ; alk. paper)
(hardcover ; alk. paper)