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E-book

Title Principles of cellular engineering : understanding the biomolecular interface / edited by Michael R. King
Published Amsterdam ; Boston : Elsevier Academic Press, [2006]
©2006
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Description 1 online resource (xv, 314 pages, 7 unnumbered pages of plates) : illustrations (some color)
Contents PART I. NEUTROPHIL ADHESION -- Adhesion of flowing neutrophils to model vessel surfaces -- Bond formation during cell compression -- A flow chamber for capillary networks -- Membrane dynamics during neutrophil recruitment -- Hydrodynamic recruitment of cells to reactive surfaces -- PART II: CELL-SUBSTRATE ADHESION -- Cell tensegrity models and cell-substrate interactions -- Use of hydrodynamic shear stress to analyze cell adhesion -- Traction forces exerted by endothelial cells -- Control of endothelial cell adhesion by mechanotransmission -- PART III. ENGINEERED BIOMIMETIC SURFACES -- Realistic atomistic modeling of protein adsorption to ceramic biomaterials -- Cell responses to micro- and nano-topography
Traction forces exerted by adherent cells / by Cynthia A. Reinhart-King and Daniel A. Hammer -- Control of endothelial cell adhesion by mechanotransmission from cytoskeleton to substrate / by Rosalind E. Mott and Brian P. Helmke -- Use of hydrodynamic shear stress to analyze cell adhesion / by David Boettiger -- Cellular tensegrity models and cell-substrate interactions / by Dimitrije Stamenović, Ning Wang, and Donald E. Ingber -- Bond formation during cell compression / by Elena Lomakina and Richard E. Waugh -- Dynamics of the neutrophil surface during emigration from blood / Thomas R. Gaborski and James L. McGrath -- Glycocalyx regulation of cell adhesion / Philippe Robert, Laurent Limozin, Anne-Marie Benoliel, Anne Pierres, and Pierre Bongrand -- Atomistic modeling of protein adsorption to ceramic biomaterials in water: a first step toward realistic simulation of the biomaterials surface in vivo / by Alan H. Goldstein -- Model cell membrane surfaces for measuring receptor-ligand interactions / by Craig D. Blanchette, Timothy V. Ratto, and Marjorie L. Longo -- A flow chamber for capillary networks: leukocyte adhesion in capillary sized, ligand-coated micropipettes / by David F.J. Tees, Prithu Sundd, and Douglas J. Goetz -- Adhesion of flowing neutrophils to model vessel surfaces: constraint and regulation by the local hemodynamic environment / Gerard B. Nash and G. Ed Rainger -- Hydrodynamic interactions between cells on reactive surfaces / Dooyoung Lee and Michael R. King -- Dynamics of platelet aggregation and adhesion to reactive surfaces under flow / Nipa A. Mody and Michael R. King
Summary This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering concepts and tools may be effectively applied to complex systems in biomedicine.-Accessible to biologists looking for new ways to model their results and engineers interested in biomedical applications -Useful to researchers in biomaterials, inflammation, and vascular biology -Excellent resource for graduate students as a textbook in cell & tissue engineering or cell mechanics courses
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cell adhesion.
Cell interaction.
Tissue engineering.
Cell Adhesion Molecules.
Cell Adhesion -- physiology.
Cell Communication.
Tissue Engineering.
Form Electronic book
Author King, Michael R., 1973-
LC no. 2005025101
ISBN 0080539637 (electronic bk.)
0123693926
9780080539638 (electronic bk.)
9780123693921