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Title Antioxidants and cardiovascular disease / edited by Martial G. Bourassa and Jean-Claude Tardif
Edition Second edition
Published New York : Springer, [2006]
Online access available from:
Springer eBooks    View Resource Record  


Description 1 online resource (xvi, 494 pages) : illustrations
Series Developments in cardiovascular medicine ; 233
Developments in cardiovascular medicine ; 233
Contents General concepts about oxidative stress / Ulf Landmesser and Helmut Drexler -- Lipoproteins and oxidation / Sotirios Tsimikas -- Pathogenesis of atherosclerosis / Juan Viles-Gonzalez, Juan J. Badimon, Valentin Fuster -- The antioxidant hypothesis / Charlene Bierl, Marc Forgione, and Joseph Loscalzo -- Reactive oxygen species as mediators of signal transduction in cardiovascular diseases / Charles Kunsch and Xilin Chen -- Biomarkers of oxidant stress in vivo : oxidative modifications of lipids, proteins and DNA / Ian A. Blair, John A Lawson, Harry Ischiropoulos and Garret A. FitzGerald -- Pharmacological compounds with antioxidant activity / Sergey Dikalov and David G. Harrison -- Antioxidant nutrients and antioxidant nutrient-rich foods against coronary heart disease / Michel de Lorgeril and Patricia Salen -- Antioxidants and chronic vascular disease : animal studies / Tillman Cyprus and Domenico Pratico -- Synthetic antioxidants and atherosclerosis : human studies / Martial G. Bourassa and Jean-Claude Tardif -- Antioxidants and endothelial function : human studies / Christian Bingelli, Isabella Sudano, Bernd van der Loo, Francesco Cosentino, Georg Noll, and Thomas F. Luscher -- Antioxidant vitamins and cardiovascular disease / Danielle Hollar and Charles H. Hennekens -- Antioxidants and restenosis after percutaneous coronary intervention : animal studies / Eric Durand, Ayman Al Haj Zen, Camille Brasselet, Antoine Lafont -- Antioxidants and restenosis after percutaneous coronary intervention : human studies / Martial G. Bourassa and Jean-Claude Tardif -- Oxidative stress in hypertension / Ernesto L. Schiffrin and Rhian M. Touyz -- Oxidative stress in the development of diabetes and its complications / Jean-Louis Chiasson, Remi Rabasa-Lhoret and Ashok K. Srivastava -- Anti-inflammatory and antioxidant functions of high density lipoproteins / Ryan E. Moore and Daniel J. Rader -- Oxidative stress in heart failure / Douglas B. Sawyer and Wilson S. Colucci -- Use of antioxidants in patients with congestive heart failure / Anique Ducharme, Jean Lucien Rouleau, Michel White
Summary Antioxidants and Cardiovascular Disease, Second Edition addresses a complex but very timely and fascinating problem in cardiovascular medicine. It is written by recognized experts in the fields of atherosclerosis and antioxidants. It should be of interest not only to academicians but also to practicing physicians. The first five chapters review the general concepts of oxidative stress and their relationship to lipid metabolism, endothelial dysfunction, genetics and transcriptional factors. The next seven chapters describe recently defined markers of oxidative stress, pharmacological compounds with antioxidant activity, natural antioxidants found in micronutrients and in nutrient-rich diets, and reviews the recent evidence for their efficacy or lack of efficacy in patients with cardiovascular disease or cardiovascular risk factors. The last seven chapters discuss the potential therapeutic benefits of antioxidants in a number of cardiovascular conditions which include atherosclerosis, restenosis after percutaneous coronary intervention, major cardiovascular risk factors such as hypertension, diabetes mellitus and dyslipidemia, and left ventricular dysfunction and congestive heart failure. Martial G. Bourassa, M.D. and Jean-Claude Tardif, M.D. are affiliated with the Montreal Heart Institute, Research Center and Department of Medicine, Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer e-books
Subject Antioxidants -- Therapeutic use.
Atherosclerosis -- Prevention.
Blood lipids -- Peroxidation.
Cardiovascular system -- Diseases -- Prevention.
Cardiovascular system -- Pathophysiology.
Cardiovascular Diseases -- prevention & control.
Antioxidants -- therapeutic use.
Oxidative Stress -- physiology.
Form Electronic book
Author Bourassa, Martial G.
Tardif, Jean-Claude.
LC no. 2005933858
ISBN 0387295526 (Cloth)
9780387295527 (Cloth)