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Title Arterial chemoreceptors / [edited by] Constancio Gonzalez, Colin A. Nurse, Chris Peers
Published [Dordrecht] : Springer, ©2009

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Description 1 online resource (xxv, 455 pages) : illustrations
Series Advances in experimental medicine and biology ; 648
Advances in experimental medicine and biology ; 648.
Contents The discovery of sensory nature of the carotid bodies / F. De Castro -- Fifty years of progress in carotid body physiology / R.S. Fitzgerald, C. Eyzaguirre and P. Zapata -- Carotid body: new stimuli and new preparations / Colin A. Nurse -- Enzyme-linked acute oxygen sensing in airway and arterial chemoreceptors / Paul J. Kemp and C. Peers -- Cysteine residues in the C-terminal tail of the human BK[Ca][alpha] subunit are important for channel sensitivity to carbon monoxide / S.P. Brazier [and others] -- Modulation of O2 sensitive K+ channels by AMP-activated protein kinase / M.L. Dallas [and others] -- Hydrogen sulfide inhibits human BK[Ca] channels / V. Telezhkin [and others] -- DDPX modifies TEA sensitivity of the Kv4 channels in rabbit carotid body chemoreceptor cells / O. Colinas [and others] -- Sustained hypoxia enhances TASK-like current inhibition by acute hypoxia in rat carotid body type-I cells / F. Ortiz, R. Iturriaga and R. Varas -- Inhibition of L-type Ca2+ channels by carbon monoxide / M.L. Dallas, J.L. Scragg and C. Peers -- Effects of the polyamine spermine on arterial chemoreception / S. Cayzac [and others] -- RT-PCR and pharmacological analysis of L-and T-type calcium channels in rat carotid body / A.I. Cáceres, E. Gonzalez-Obeso, C. Gonzalez and A. Rocher -- Functional characterization of phosphodiesterases 4 in rat carotid body: effect of oxygen concentrations / A.R. Nunes, J.R. Batuca and E.C. Monteiro -- Calcium sensitivity for hypoxia in PGNs with PC-12 cells in co-culture / G.P. Patel, S.M. Baby, A. Roy and S. Lahiri -- Modification of relative gene expression ratio obtained from real time qPCR with whole carotid body by using mathematical equations / J.H. Kim and J.L. Carroll -- Neurotransmitters in carotid body function: the case of dopamine / R. Iturriaga, J. Alcayaga and C. Gonzalez -- Adenosine in peripheral chemoreception: new insights into a historically overlooked molecule / S.V. Conde, E.C. Monteiro, A. Obeso and C. Gonzalez
The A2B-D2 receptor interaction that controls carotid body catecholamines release locates between the last two steps of hypoxic transduction cascade / S.V. Conde, A. Obeso, E.C. Monteiro and C. Gonzalez -- Benzodiazepines and GABA-GABA[A] receptor system in the cat carotid body / A. Igarashi, N. Zadzilka and M. Shirahata -- Evidence for histamine as a new modulator of carotid body chemoreception / R. Del Rio, E.A. Moya, J. Alcayaga and R. Iturriaga -- Fluoresceinated peanut agglutinin (PNA) is a marker for live O2 sensing glomus cells in rat carotid body / I. Kim, D.J. Yang, D.F. Donnelly and J.L. Carroll -- Neuroglobin in aging carotid bodies / V. Verratti [and others] -- Oxygen sensing and the activation of the hypoxia inducible factor 1 (HIF-1) / Joachim Fandrey and Max Gassmann -- Upregulation of erythropoietin and its receptor expression in the rat carotid body during chronic and intermittent hypoxia / S.Y. Lam, G.L. Tipoe and M.L. Fung -- Iron chelation and the ventilatory response to hypoxia / Mieczyslaw Pokorski [and others] -- Systemic effects resulting from carotid body stimulation / Prem Kumar -- Bicarbonate-regulated soluble adenylyl cyclase (sAC) mRNA expression and activity in peripheral chemoreceptors / A.R. Nunes, E.C. Monteiro, S.M. Johnson and E.B. Gauda -- Developmental maturation of chemosensitivity to hypoxia of peripheral arterial chemoreceptors / Estelle B. Gauda, John L. Carroll and David F. Donnelly -- Physiological carotid body denervation during aging / C. Di Giulio [and others] -- Does ageing modify ventilatory responses to dopamine in anaesthetised rats breathing spontaneously? / T.C. Monteiro, A. Obeso, C. Gonzalez and E.C. Monteiro -- The role of the carotid bodies in the counter-regulatory response to hypoglycemia / Denham S. Ward, William A. Voter and Suzanne Karan -- The respiratory responses to the combined activation of the muscle metaboreflex and the ventilatory chemoreflex / C.K. Lykidis, P. Kumar and G.M. Balanos
Cardiovascular responses to hyperoxic withdrawal of arterial chemosensory drive / Patricio Zapata [and others] -- Time-dependence of hyperoxia-induced impairment in peripheral chemoreceptor activity and glomus cell calcium response / J.L Carroll [and others] -- Long-term regulation of carotid body function: acclimatization and adaptation / N.R. Prabhakar [and others] -- Effects of intermittent hypoxia on blood gases plasma catecholamine and blood pressure / M.C. Gonzalez-Martin [and others] -- Cardioventilatory acclimatization induced by chronic intermittent hypoxia / R. Iturriaga [and others] -- Ventilatory drive is enhanced in male and female rats following chronic intermittent hypoxia / E. Edge, J.R. Smelly, A. Bradford and K.D. O'Halloran -- Contrasting effects of intermittent and continuous hypoxia on low O2 evoked catecholamine secretion from neonatal rat chromaffin cells / Dangjai Souvannakitti, Ganesh K. Kumar, Aaron Fox and Nanduri R. Prabhakar -- Hypoxic pulmonary vasoconstriction / A. Mark Evans and Jeremy P.T. Ward -- Impact of modulators of mitochondrial ATP-sensitive potassium channel (mitoK[ATP]) on hypoxic pulmonary vasoconstriction / R. Paddenberg [and others] -- Oxygen sensing in the brain / Frank L. Powell, Cindy B. Kim, Randall S. Johnson and Zhenxing Fu -- The central respiratory chemoreceptor: where is ti located? / Y. Okada [and others] -- Anatomical architecture and responses to acidosis of a novel respiratory neuron group in the high cervical spinal cord (HCRG) of the neonatal rat / Y. Okada [and others]
Systemic inhibition of the Na+/H+ exchanger type 3 in intact rats activated brainstem respiratory regions / R. Pasaro [and others] -- Nitric oxide in the solitary tract nucleus (STn) modulates glucose homeostasis and FOS-ir expression after carotid chemoreceptor stimulation / M. Lemus [and others] -- Airway receptors and their reflex function / J. Yu -- Airway chemosensitive receptors in vagus nerve perform neuro0immune interaction for lung-brain communication / H.F. Li and J. Yu -- The role of NOX2 and "novel oxidases" in airway chemoreceptor P2 sensing / Ernest Cutz, Jie Pan and Herman Yeger -- Recruitment of GABA[A] receptors in chemoreceptor pulmonary neuroepithelial bodies by prenatal nicotine exposure in monkey lung / X.W. Fu and E.R. Spindel
Summary The carotid body arterial chemoreceptors constitute unique sensory receptors capable of rapidly monitoring the levels of arterial blood oxygen and carbon dioxide. Whenever necessary they initiate homeostatic reflexes aimed to correct the detected deviations. Chemoreceptor cells of the carotid body constitute ideal models to study the entire processes of O2-sensing as well as CO2-sensing. The present book represents an updated review of the physiology of the carotid body chemoreceptors. Most important, the book provides the trends in the field as it contains results in the topics that are at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, it contains data from studies carried in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells as well as on central CO2/pH chemoreceptors. Arterial Chemoreceptors should be considered as a prime source of information and as a guideline to every researcher in the field of arterial chemoreception in the years to come. It is also an important source of information for researchers and clinicians in the fields of hypoxic pulmonary vasoconstriction and pulmonary hypertension as well as for researchers in the field of erythropoietin and central chemoreceptors
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer - LINK
Subject Chemoreceptors.
Respiration -- Regulation.
Carotid Body -- physiology
Ion Channels -- phys
Oxygen -- metabolism
Chemoreceptor Cells -- physiology
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Chemoreceptors.
Respiration -- Regulation.
Sciences de la vie.
Biomédecine.
Chemoreceptors
Respiration -- Regulation
Genre/Form proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congrès.
Form Electronic book
Author Gonzalez, Constancio
Nurse, Colin A
Peers, C. (Christopher)
ISBN 9789048122592
9048122597
9789048122585
9048122589