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E-book

Title Oral lipid-based formulations : enhancing the bioavailability of poorly water-soluable drugs / [edited by] David J. Hauss
Published New York, NY : Informa Healthcare USA, [2007]
©2007
Online access available from:
ProQuest Ebook Central (owned titles)    View Resource Record  

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Description 1 online resource (1 volume)
Series Drugs and the pharmaceutical sciences ; v. 170
Drugs and the pharmaceutical sciences ; v. 170
Contents Currently marketed oral lipid-based dosage forms : drug products and excipients / Robert Strickley -- Feasibility assessment for scaling bench-top prototype lipid-based formulations to initial phase I/II clinical trial batches / Paul Sirois -- Lipid-based excipients for oral drug delivery / Lowell Gibson -- Process and manufacturing considerations and final characterization of oral lipid-based formulations / Bill Bowtie -- Liquid self-micro-emulsifying drug delivery systems (SMEDDS) / Annette Mullertz -- Lipid based isotropic solutions : design considerations / Navnit Shah -- Lipid-based self-emulsifying solid dispersions / Abu Serajuddin -- Preclinical in vivo evaluation of oral lipid-based formulations / Chris Porter, Bill Charman -- Physiological processes governing the gastrointestinal absorption of lipids and lipophilic xenobiotics / Patrick Tso -- Characterizing release from lipid-based formulations / Jennifer Dressman -- Using in vitro dynamic lipolysis modeling as a tool for exploring IVIVC relationships for oral lipid-based formulations / Annette Mullertz -- Case study: rational development of self-emulsifying formulations for improving the oral bioavailability of poorly soluble, lipophilic drugs / Ping Gao -- Design and development of supersaturatable SEDDS (S-SEDDS) formulations for enhancing the gastrointestinal absorption of poorly soluble drugs / Ping Gao
Summary Oral lipid-based formulations have the capacity to facilitate gastrointestinal absorption and reduce or eliminate the effect of food on the absorption of poorly water-soluble, lipophilic drugs. This book provides a summary of the theoretical and practical aspects of oral lipid-based formulations for use in industry
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Drugs -- Dosage forms.
Drugs -- Solubility.
Lipids -- Therapeutic use.
Solutions (Pharmacy)
Biological Availability.
Solubility -- drug effects.
Dosage Forms.
Drug Administration Routes.
Drug Delivery Systems -- methods.
Form Electronic book
Author Hauss, David J.
ISBN 1420017268 (electronic bk.)
9781420017267 (electronic bk.)