| Description |
1 online resource (365 pages) |
| Contents |
Part I. Introduction -- Proteins of the Nucleolus: An Introduction / Danton H. O'Day, Andrew Catalano -- Part II. The Nucleolus and Nucleolar Proteins -- Functional Consequences of Nuclear and Nucleolar Architecture / Eva Bártová, Lenka Stixová -- rDNA and Nucleologenesis in Drosophila / Patrick DiMario, Allison James, Himanshu Raje -- The Nucleolus of Dictyostelium and Other Lower Eukaryotes / Andrew Catalano, Danton H. O'Day -- Human rDNA Genes: Identification of Four Fractions, Their Functions and Nucleolar Location / Nataliya A. Lyapunova, Nataliya N. Veiko, Lev N. Porokhovnik -- Chromatin Organization and the Mammalian Nucleolus / Attila Németh, Gernot Längst -- Chaperones and Multitasking Proteins in the Nucleolus / Mohamed Kodiha, Ursula Stochaj -- Part III. Nucleolar Protein Translocation -- Nucleolar Localization/Retention Signals / Eugene V. Sheval, Yana R. Musinova -- Nucleolar Transport of Putative GTPase GNL1 and Related Proteins / S. Mahalingam, M.R.K. Subba Rao, Neelima Boddapati, T. Indu Jose, Debduti Datta -- Nucleolar Protein Anchoring and Translocation / Krzysztof Staroń, Agnieszka Girstun -- Part IV. Nucleolar Proteins and Disease -- The Nucleolus as a Stress Response Organelle / Mikael S. Lindström, Leena Latonen -- The Nucleolar Aspect of Breast Cancer / Judy Yan, Damu Tang -- Cysteine Proteinase Inhibitors in the Nucleus and Nucleolus in Activated Macrophages / Nataša Kopitar-Jerala -- Nucleolar Proteins and Cancer: The Roles of Aurora A-Interacting Nucleolar Proteins in Mitosis and Cancer / Jyoti Iyer, Saili Moghe, Manabu Furukawa, Ming-Ying Tsai -- Nucleolar Transplantation and Human Embryogenesis / Helena Fulka, Alena Langerova, Stanislava Martinkova, Josef Fulka Jr. -- Part V. Conclusions -- The Nucleolus: From Its Formation to the Future / Danton H. O'Day, Andrew Catalano |
| Summary |
This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Nucleolus.
|
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Nuclear proteins.
|
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Cell Nucleolus
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Nuclear Proteins
|
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SCIENCE -- Life Sciences -- Biochemistry.
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Nuclear proteins
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Nucleolus
|
| Form |
Electronic book
|
| Author |
O'Day, Danton H.
|
|
Catalano, Andrew
|
| LC no. |
2013932350 |
| ISBN |
9789400758186 |
|
9400758189 |
|
1299407803 |
|
9781299407800 |
|
