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E-book
Author Torday, John S.

Title Evolutionary Biology : Cell-Cell Communication, and Complex Disease
Published Hoboken : John Wiley & Sons, 2012
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Description 1 online resource (186 pages)
Contents EVOLUTIONARY BIOLOGY, CELL-CELL COMMUNICATION, AND COMPLEX DISEASE; CONTENTS; PREFACE; ABOUT THE AUTHORS; 1: THE CELLULAR ORIGIN OF VERTEBRATES; THE ORIGINS OF UNICELLULAR LIFE ON EARTH; PROKARYOTES VERSUS EUKARYOTES; COEVOLUTION OF TRAITS; CHOLESTEROL FACILITATES LIPID RAFTS FOR CELL-CELL COMMUNICATION; THE ENDOMEMBRANE SYSTEM; THE CELLULAR MECHANISM OF EVOLUTION; WHY EVOLVE?; CELL-CELL COMMUNICATION AND AGING; 2: REDUCING LUNG PHYSIOLOGY TO ITS MOLECULAR PHENOTYPES; HORMONAL ACCELERATION OF LUNG DEVELOPMENT; NEUTRAL LIPID TRAFFICKING AND LUNG EVOLUTION
OTHER EXAMPLES OF CELLULAR COOPERATIVITYSUMMARY; 3: A CELL-MOLECULAR STRATEGY TO SOLVING THE EVOLUTIONARY PUZZLE; RATIONALE FOR CELL-MOLECULAR EVOLUTION; MECHANISM OF MAMMALIAN LUNG DEVELOPMENT; AVIAN LUNG STRUCTURE-FUNCTION RELATIONSHIP: THE EXCEPTION THAT PROVES THE RULE; DOES ONTOGENY RECAPITULATE PHYLOGENY? THE ROLE OF PTHRP IN LUNG DEVELOPMENT; INTERRELATIONSHIP BETWEEN PTHRP, DEVELOPMENT, PHYSIOLOGY, AND REPAIR: IS REPAIR A RECAPITULATION OF ONTOGENY AND PHYLOGENY?; 4: THE EVOLUTION OF CELL-CELL COMMUNICATION; CELL-CELL COMMUNICATION AS THE MECHANISTIC BASIS FOR EVOLUTIONARY BIOLOGY
SEXUAL DIMORPHISM OF LUNG DEVELOPMENT: A CASE STUDY IN CELL-CELL COMMUNICATION AND EVOLUTIONARY PLASTICITYANDROGEN AFFECTS THE EXPRESSION OF GROWTH FACTORS INVOLVED IN LUNG DEVELOPMENT; EVIDENCE FOR AN ASSOCIATION BETWEEN STEROID-RESISTANT/RESPONSIVE PHENOTYPES AND HUMAN LYMPHOCYTE ANTIGEN (HLA) HAPLOTYPES; 5: HOW TO INTEGRATE CELL-MOLECULAR DEVELOPMENT, HOMEOSTASIS, ECOLOGY, AND EVOLUTIONARY BIOLOGY: THE MISSING LINKS; NEUTRAL THEORY VERSUS INTELLIGENT DESIGN; INTERNAL SELECTION THEORY; THE COUNTERINTUITIVE NATURE OF PHYSIOLOGY AND SOLUTION TO THE DEAD SEA SCROLLS PUZZLE
THE CONTINUUM FROM MICROEVOLUTION TO MACROEVOLUTIONcis REGULATION AND ADAPTIVE EVOLUTION; EVOLUTION OF cis REGULATORY MECHANISMS; 6: FROM CELL-CELL COMMUNICATION TO THE EVOLUTION OF INTEGRATED PHYSIOLOGY; CELL-CELL SIGNALING AND ALVEOLAR DEVELOPMENT: A REDUCTIONIST APPROACH TO THE EVOLUTION OF PHYSIOLOGIC TRAITS; AN INTEGRATED, EMPIRIC, MIDDLE-OUT APPROACH TO PHYSIOLOGY; A MOLECULAR EVOLUTIONARY LINK BETWEEN THE LUNG AND THE KIDNEY?; THE BERNER HYPOTHESIS AND EMERGENCE OF THE ADIPOCYTE: THE EVOLUTIONARY ORIGINS OF THE LIPOFIBROBLAST; LUNG BIOLOGY AS A CIPHER FOR EVOLUTION
THE DARWINIAN BIOLOGIC SPACETIME CONTINUUM AND EINSTEIN'S VISION OF THE UNIVERSEREVERSE ENGINEERING OF PHYSIOLOGIC TRAITS AS A PORTAL FOR VIEWING EVOLUTION; CELL-CELL COMMUNICATION AS THE BASIS FOR THE EVOLUTION OF METAZOANS; UNDERSTANDING LUNG EVOLUTION FROM THE MIDDLE OUT; THE CELL-CELL COMMUNICATION MODEL OF LUNG EVOLUTION TRACES CONTEMPORARY PHENOTYPES BACK TO ANCESTRAL PHENOTYPES; PREDICTIVE VALUE OF THE LUNG CELL-CELL COMMUNICATION MODEL FOR UNDERSTANDING THE EVOLUTION OF PHYSIOLOGIC SYSTEMS
Summary An integrative view of the evolution of genetics and the natural worldEven in this advanced age of genomics, the evolutionary process of unicellular and multicellular organisms is continually in debate. Evolutionary Biology, Cell-Cell Communication, and Complex Disease challenges current wisdom by using physiology to present an integrative view of the nature, origins, and evolution of fundamental biological systems. Providing a deeper understanding of the way genes relate to the traits of living organisms, this book offers useful information applying evolutionary biology, functional genomics, a
Notes Do stretch effects on pthrp expression reflect its role in adapting to gravity?
Print version record
Subject Cell interaction.
Molecular evolution.
Molecular genetics.
Pathology, Molecular.
Form Electronic book
Author Rehan, Virender K.
ISBN 1118130421 (electronic bk.)
9781118130421 (electronic bk.)