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E-book
Author Chiappelli, Francesco, author

Title Fundamentals of evidence-based health care and translational science / Francesco Chiappelli
Published Berlin : Springer, 2014
Online access available from:
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Description 1 online resource (xxvii, 394 pages) : illustrations (some color)
Contents Fundamental Implications for Clinical Practice -- Translational Effectiveness in the Context of Translational Science -- Comparative Effectiveness Analysis and Evidence-Based Decisions -- Methodology I: The Best Available Evidence -- Methodology II: Sampling and Assessment of the Evidence -- Methodology III: Systematic Evaluation of the Statistical Analysis: Data Analysis in Research Synthesis -- Optimizing Clinical Practice-Based Patient-Centered Outcomes Research -- Getting and Understanding Data -- Obtaining Data -- Describing and Analyzing Data -- Translational Effectiveness Analysis -- Optimizing Clinical Outcomes by Individualizing Observations -- Evaluation in Patient-Centered Outcomes Research -- Translational Effectiveness in Practice-Based Patient-Centered Outcomes Research
Summary Comparative effectiveness research - the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options - is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing 'complex' systematic reviews, 'cumulative' meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research
Bibliography Includes bibliographical references (pages 361-384) and index
Notes Print version record
Subject Drugs -- Effectiveness -- Research -- Methodology.
Comparative Effectiveness Research.
Evidence-Based Medicine.
Decision Making.
Outcome Assessment (Health Care)
Form Electronic book
ISBN 9783642418570 (electronic bk.)
3642418570 (electronic bk.)