Limit search to available items
Book Cover
E-book
Author Holmes, Frederic Lawrence

Title Reconceiving the gene : Seymour Benzer's adventures in phage genetics / Frederic Lawrence Holmes ; edited by William C. Summers
Published New Haven : Yale University Press, ©2006

Copies

Description 1 online resource (ix, 334 pages) : illustrations
Contents Classical mendelian genetics -- Genetics and the phage biologists -- The physicist becomes a phage biologist -- To Paris and back -- Teaching and research at Purdue -- Entering the rII region -- Crossing into the fine structure -- Is gene a dirty word? -- The survival of the "gene."
Summary A fascinating and detailed chronicle, "Reconceptualizing the Gene" relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments and discoveries are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, Frederic Lawrence Holmes reconstructs how the former physicist initiated his work in phage biology, and how he accomplished his landmark investigation. The book follows Benzer's investigative pathway as his research unfolded and shifted, and as he adapted to opportunities or disappointments as they arose. The story of Benzer's creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise
Bibliography Includes bibliographical references (pages 303-329) and index
Notes English
Print version record
Subject Benzer, Seymour.
SUBJECT Benzer, Seymour fast
Subject Geneticists -- United States -- Biography
Bacteriophages -- Genetics.
Viral genetics -- History
Microbial genetics.
Gene mapping.
Bacterial genomes.
Bacteriophage T4 -- genetics
Genetics, Microbial
Chromosome Mapping
Genome, Bacterial
SCIENCE -- Life Sciences -- Genetics & Genomics.
BIOGRAPHY & AUTOBIOGRAPHY -- Science & Technology.
Microbial genetics
Gene mapping
Bacterial genomes
Bacteriophages -- Genetics
Geneticists
Viral genetics
Genetica.
Microbiologie.
Bacteriofagen.
United States
Genre/Form Biographies
History
Biographies.
Biographies.
Form Electronic book
Author Summers, William C
ISBN 9780300129700
030012970X
9786611730475
6611730478