| Description |
1 online resource (xviii, 467 pages) : illustrations |
| Series |
Ophthalmology research |
|
Ophthalmology research.
|
| Contents |
1 Aquaporins and water transport in the cornea / Alan S. Verkman -- 2 Roles of corneal epithelial ion transport mechanisms in mediating responses to cytokines and osmotic stress / Peter S. Reinach, José E. Capó-Aponte, Stefan Mergler, and Kathryn S. Pokorny -- 3 Vitamin C transport, delivery, and function in the anterior segment of the eye / Ram Kannan and Hovhannes J. Gukasyan -- 4 Mechanisms of aqueous humor formation: cellular model of aqueous flow / Chi-wai Do, Chi-wing Kong, Chu-yan Chang, Mortimer M. Civan, and Chi-ho To -- 5 Membrane transporters: new roles in lens cataract / Paul J. Donaldson and Julie Lim -- 6 Lens Na+, K+-ATPase / Nicholas A. Delamere and Shigeo Tamiya -- 7 Pathophysiology of pericyte-containing retinal microvessels: roles of ion channels and transporters / Donald G. Puro -- 8 Molecular mechanisms of the inner blood-retinal barrier transporters / Masatoshi Tomi and Ken-ichi Hosoya -- 9 Regulation and transport in the RPE / Adnan Dibas and Thomas Yorio -- 10 Glucose transporters in the retinal pigment epithelium / Lawrence J. Rizzolo -- 11 Ca2+ channels in the retinal pigment epithelium: modulators of retinal pigment epithelium function and communication with neighboring tissues / Olaf Strauss -- 12 Taurine transport pathways in the outer retina in relation to aging and disease / Ali A. Hussain and John Marshall -- 13 P-Glycoprotein expression and function in the retinal pigment epithelium / Paul A. Constable, John G. Lawrenson, and N. Joan Abbott -- 14 The retinal rod NCKX1 and cone/ganglion cell NCKX2 Na+/CA2+-K+ exchangers / Paul P.M Schnetkamp et al -- 15 Excitatory amino acid transporters in the retina / Vijay Sarthy and David Pow -- 16 Localization and function of gamma aminobutyric acid transporter 1 in the retina / Giovanni Casini -- 17 Biochemical defects associated with genetic mutations in the retina-specific ABC transporter, ABCR, and macular degenerative diseases / Esther E. Biswas-Fiss -- 18 Glutamate transporters and retinal disease and regulation / Nigel L. Barnett and Natalie D. Bull -- 19 Glutamate transport in retinal glial cells during diabetes / Erica L. Fletcher and Michelle M. Ward -- 20 The emerging significance of drug transporters and metabolizing enzymes to ophthalmic drug design / Mayssa Attar and Jie Shen -- 21 Barriers in ocular drug delivery / Sriram Gunda, Sudharshan Hariharan, Nanda Mandava, and Ashim K. Mitra -- 22 Ophthalmic applications of nanotechnology / Swita Raghava, Gaurav Goel, and Uday B. Kompella -- 23 Vitamin C transporters in the retina / Vadivel Ganapathy, Sudha Ananth, Sylvia B. Smith, and Pamela M. Martin -- 24 The plasma membrane transporters and channels of corneal endothelium / Jorge Fischbarg |
| Summary |
This exceptionally important new work represents recent discoveries and advancements in the study of ocular transporters and their roles in ocular physiology, pathology, and drug delivery. Transporters are found on the membranes of cells and play a key role in transmitting signals between cells. In Ocular Transporters in Ophthalmic Diseases and Drug Delivery, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volu |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Biological transport.
|
|
Eye -- Physiology
|
|
Eye -- Diseases.
|
|
Drug targeting.
|
|
Ocular Physiological Phenomena
|
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Drug Delivery Systems
|
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Eye Diseases -- drug therapy
|
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Eye Diseases -- physiopathology
|
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Ion Transport
|
|
Membrane Transport Proteins
|
|
Biological Transport
|
|
Eye Diseases
|
|
MEDICAL -- Neuroscience.
|
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PSYCHOLOGY -- Neuropsychology.
|
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Biological transport
|
|
Drug targeting
|
|
Eye -- Diseases
|
|
Eye -- Physiology
|
| Form |
Electronic book
|
| Author |
Tombran-Tink, Joyce.
|
|
Barnstable, Colin J.
|
| ISBN |
9781597453752 |
|
1597453757 |
|
9781588299581 |
|
1588299589 |
|
