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Title Molecular principles of fungal pathogenesis / edited by Joseph Heitman, Scott G. Filler, John E. Edwards, Jr., and Aaron P. Mitchell
Published Washington, D.C. : ASM Press, ©2006
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Description 1 online resource (xvi, 684 pages) : illustrations (some color), map
Series Monograph, ASM Press
Monograph, ASM Press
Contents Fungal biofilms : agents of disease and drug resistance / Gordon Ramage, Mahmoud A. Ghannoum, and José L. López-Ribot -- Molecular basis of fungal adherence to endothelial and epithelial cells / Scott G. Filler, Donald C. Sheppard, and John E. Edwards, Jr. -- Molecular principles of antifungal drug resistance / Dominique Sanglard and Theodore C. White -- Heterologous hosts and the evolution and study of fungal pathogenesis / Eleftherios Mylonakis, Stephen B. Calderwood, and Frederick M. Ausubel -- Amoeba and slime mold: hosts of virulence evolution / Arturo Casadevall -- Aspergillus nidulans : a model for elucidation of Aspergillus fumigatus secondary metabolism / Nancy Keller -- Saccharomyces cerevisiae : an emerging and model pathogenic fungus / John H. McCusker -- Fungal-bacterial interactions / Deborah A. Hogan and Roberto Kolter -- Amphibian chytridiomycosis as an emerging infectious disease of wildlife : what can we learn from the earliest diverging fungi? / Timothy Y. James and Rytas Vilgalys -- Cryptococcus neoformans : a sugar-coated killer / John R. Perfect -- Toward a molecular understanding of Candida albicans virulence / Frank C. Odds, Neil A.R. Gow, and Alistair J.P. Brown -- Molecular determinants of Histoplasma capsulatum pathogenesis / Jon P. Woods -- Molecular determinants of virulence in Aspergillus fumigatus / Judith C. Rhodes and Axel A. Brakhage -- Pathogenesis of pneumocystis / A. George Smulian and Melanie T. Cushion
Fungal interactions with leukocytes / Mairi C. Noverr [and others] -- Fungal vaccine development / Joshua D. Nosanchuk and George S. Deepe Jr. -- Molecular immunopathogenesis of innate host defense against chronic disseminated (hepatosplenic) candidiasis / Thomas J. Walsh [and others] -- Studying fungal virulence using genomics / Michael C. Lorenz -- Future of functional genomics of Histoplasma capsulatum / Anita Sil and Lena Hwang -- Functional genomic approaches to fungal pathogenesis, drug target validation, and antifungal drug discovery / Ainslie B. Parsons, Howard Bussey, and Charles Boone -- Genetic and proteomic analysis of fungal virulence / Jennifer K. Lodge and Michael C. Lorenz -- Genomic perspectives on the fungal kingdom / Jason E. Stajich and Fred S. Dietrich
Fungal molecular pathogenesis : what can it do and why do we need it? / John R. Perfect and Arturo Casadevall -- Sex, MAT, and the evolution of fungal virulence / James A. Fraser and Joseph Heitman -- Postgenomic strategies for genetic analysis : insight from Saccharomyces cerevisiae and Candida albicans / Clarissa J. Nobile and Aaron P. Mitchell -- Candida albicans hypha formation and virulence / Paula Sundstrom -- The conversion from classical studies in fungal pathogenesis to the molecular era / Kyung J. Kwon-Chung and Brian L. Wickes -- Mating and parasexual genetics in Candida albicans / Mathew Miller and Alexander Johnson -- The mating-type locus and mating of Candida albicans and Candida glabrata / David R. Soll -- Evolution of human pathogenic fungi : phylogenies and species / John W. Taylor -- Establishment of cell identity in pathogenic fungi / Christina M. Hull -- Signal transduction in the interactions of fungal pathogens and mammalian hosts / Malcolm Whiteway and Catherine Bachewich -- Function and regulation of adhesin gene families in Saccharomyces cerevisiae, Candida albicans, and Candida glabrata / Irene Castaño, Alejandro de las Peñas, and Brendan P. Cormack
Virulence mechanisms of coccidioides / Garry T. Cole [and others] -- Blastomyces dermatitidis cell surface determinants and their application in vaccine development / Bruce Klein -- Virulence factors in black molds with emphasis on melanin, chitin, and Wangiella as a molecularly tractable model / Paul J. Szaniszlo -- Zygomycetes as agents of infectious disease in humans / Ashraf S. Ibrahim and Brad Spellberg -- Signaling pathways in the dimorphic human fungal pathogen Penicillium marneffei / Alex Andrianopoulos and Sophie Zuber -- Innate humoral immunity to fungi / Thomas R. Kozel -- Innate and acquired cellular immunity to fungi / Luigina Romani -- Acquired antibody-mediated immunity to fungi / Liise-anne Pirofski and Arturo Casadevall -- Site-specific mucosal immunity to fungi : lessons learned from Candida albicans applied to other fungi / Paul L. Fidel, Jr. and Beatriz Finkel-Jimenez -- Intracellular pathogenesis of Histoplasma capsulatum / Simon L. Newman -- Interactions of immune cells with the facultative intracellular pathogen Cryptococcus neoformans / Lauren E. Yauch and Stuart M. Levitz
Summary Annotation provides a state & ndash;of & ndash;the & ndash;art review of medical mycology compiled by the leading researchers in the field;presents a selection of chapters covering immunological aspects of infection;captures the excitement of recently completed genome projects and their impact on the understanding of fungal biology and virulence;examines the recent advances in the development of fungal vaccines;features an in & ndash;depth analysis of the host & ndash;pathogen relationship
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Histology, Pathological.
Pathogenic fungi -- Molecular aspects.
Fungi -- pathogenicity.
Fungi -- genetics.
Fungi -- immunology.
Genome, Fungal.
Mycoses.
Form Electronic book
Author Edwards, John E., editor
Filler, Scott G., editor
Heitman, Joseph, editor
Mitchell, Aaron Peter, editor
ISBN 1555815774 (electronic bk.)
9781555815776 (electronic bk.)