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E-book

Title Advances in medicine and biology. Volume 43 / Leon V. Berhardt, editor
Published New York : Nova Science Publishers, ©2012

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Description 1 online resource
Contents ADVANCES IN MEDICINE AND BIOLOGY VOLUME 43; ADVANCES IN MEDICINE AND BIOLOGY VOLUME 43; Contents ; Preface ; Paralysis in ALS Patients Pathogenesis, Assessment and Treatment ; Abstract; Introduction ; Epidemiology ; Sporadic ALS ; Familial ALS ; Etiopathogenesis ; Genetic Factors ; Environmental Factors ; Excitotoxicity ; Oxidative Stress and Apoptosis ; Lack of Neurotrophic Factors ; Immune Events and Neuroinflammation ; Defective Autophagy ; Exogenous Toxicity ; Neuropathology ; Brain ; Brainstem ; Corticospinal Tract ; Spinal Cord ; Peripheral Nervous System; Muscle; Clinical Signs
Clinical Features of Variant Disorders Diagnosis ; Clinical Criteria ; Neurophysiological Methods ; Conventional Electromyography ; Nerve Conduction Studies ; Transcranial Magnetic Stimulation ; Neuroimaging Techniques ; Laboratory Exams ; Muscle biopsy ; Biochemical Assays ; Differential Diagnoses ; Functional Assessment; Global Functional Scales ; The Appel ALS Rating Scale ; The ALS Severity Scale (ALSSS) ; ALS Functional Rating Scale ; Somatic Muscle Strength Assessment ; Manual Muscle Testing ; Maximal Voluntary Isometric Contraction ; Quantitative Electromyography
Respiratory Muscle Function Assessment Swallowing Assessment ; Speech Assessment ; Treatment; Pathogenetic Treatment ; Neuropharmacological Strategies ; Excitotoxicity ; Oxidative Stress and Apoptosis ; Neurotrophic Factors ; Neuroinflammation ; Autophagy ; Neurobiological Strategies ; Gene Therapy; Stem Cell Therapy ; Neurophysiological Strategies ; Repetitive Transcranial Magnetic Stimulation ; Symptomatic Treatment ; Pharmacological Strategies ; Non Pharmacological Strategies ; Physical Exercise ; Respiratory Treatment; Respiratory Exercises ; Mechanical Ventilation
Supportive Respiratory Care Swallowing Treatment ; Sialorrhea ; Speech Treatment ; Conclusion; References; Targeting Testosterone Pathways in Prostate Cancer Treatment ; Abstract ; Biology of Testosterone in Prostate Cancer ; 1. Androgen Synthesis and the Androgen Receptor Regulatory Pathway ; 2. Estrogen Receptors in Prostate Cancer ; 3. Prostate Cancer Prevention ; 1.) Finasteride ; 2.) Dutasteride; Androgen-Deprivation Therapy (ADT) ; 1.) Orchiectomy ; 2.) Estrogen; 3.) GnRH-A ; 4.) GnRH Antagonists ; 5.) Androgen Receptor Antagonists (ARAs) ; 6.) CYP17 Inhibitors; Ketoconazole
Abiraterone Acetate TAK-700 (Orteronel) ; 7.) AR Antagonists ; MDV3100 ; BMS-641988 ; Small Molecule Modulators ; 8.) Dual CYP17 Inhibitor and AR Antagonist ; 9.) Glucocorticoids; 2. Early-Stage Prostate Cancer ; 1.) ADT as Primary Therapy ; 2.) ADT with Radiotherapy ; 3.) ADT with Brachytherapy ; 4.) ADT with Surgery ; 3. Metastatic Castration-Sensitive Disease ; 1.) Antiandrogen Monotherapy; 2.) Combined Androgen Blockade ; 3.) ADT with Chemotherapy ; 4.) ADT and Vaccine ; 4. Timing of ADT in Metastatic Castration-Sensitive Prostate Cancer ; 1.) Immediate vs. Deferred Therapy
Notes Includes index
Title page of PDF version (Ebsco; viewed on April 4, 2013)
Subject Clinical medicine.
Biology -- Research.
Clinical Medicine
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Biology -- Research
Clinical medicine
Form Electronic book
Author Berhardt, Leon V
ISBN 9781621008897
1621008894