| Description |
1 online resource (1 streaming video file (36 min.) : color, sound) |
| Series |
Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, 2056-452X |
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Henry Stewart talks. Biomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease
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| Contents |
Contents: Members of the Eph receptor and ephrin ligand families and specificity of binding interactions -- Domain structure of Eph receptors and ephrins -- Eph receptor-ephrin interactions -- Dimerization, tetramerization and further clustering in Eph-ephrin signaling -- Tyrosine phosphorylation in Eph-ephrin activation -- Modes of signal termination -- Eph-ephrin signaling pathways affecting the actin cytoskeleton and cell adhesion: Cell repulsion versus adhesion/attraction, pathways that are activated downstream of Eph receptors -- Main Eph effects on cell behavior: shaping and positioning cellular processes and cell migration -- Eph receptors in topographic mapping in the visual system -- Eph receptors in the organization of axonal projections -- Eph receptors in angiogenesis and lymphangiogenesis -- Eph receptors in stem cell proliferation and differentiation -- Eph receptors in cancer -- Eph receptors as drug targets |
| Notes |
Animated audio-visual presentation with synchronized narration |
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Title from title frames |
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Mode of access: World Wide Web |
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System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+ |
| Subject |
Cellular signal transduction.
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Ephrins.
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Receptor Protein-Tyrosine Kinases.
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Receptors, Eph Family.
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| Genre/Form |
Video recordings.
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| Form |
Streaming video
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