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Book Cover
Streaming video
Author Fan, Qing R., (Columbia University, USA)

Title Extracellular domain structures from calcium-sensing and GABA(B) receptors / Qing R. Fan
Published London : Henry Stewart Talks, 2019
Online access available from:
HSTalks Biomedical & Life Sciences Collection    View Resource Record  


Description 1 online resource (1 streaming video file (36 min.) : color, sound)
Series Structural and functional insights into GPCR signalling, 2056-452X
Henry Stewart talks. Biomedical & life sciences collection. Structural and functional insights into GPCR signalling
Contents Contents: Crystal structures of human GABA(B) receptor extracellular domain in multiple functional states -- Agonist vs. antagonist recognition -- Identification of novel heterodimer interface associated with receptor activation -- Crystal structures of human CaSR in the inactive and active conformations -- Discovery of L-amino acids as orthosteric agonists of CaSR -- Identification of Ca2+ and PO43 binding sites in CaSR -- Universal activation mechanism of class C GPCRs
Notes Animated audio-visual presentation with synchronized narration
Title from title frames
Restricted Access restricted to subscribers
Notes Mode of access: World Wide Web
Subject Amino acids -- Receptors
Calcium -- Receptors
Cellular signal transduction
G proteins -- Receptors
Binding Sites
GABA-B Receptor Agonists
GABA-B Receptor Antagonists
Protein Conformation
Receptors, Calcium-Sensing -- chemistry
Receptors, Calcium-Sensing -- metabolism
Receptors, GABA-B -- chemistry
Receptors, GABA-B -- metabolism
Receptors, G-Protein-Coupled