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Title Calcium entry channels in non-excitable cells / edited by Juliusz Ashot Kozak and James W. Putney, Jr
Published Boca Raton, FL : CRC Press, [2017]
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Description 1 online resource (328 pages) : illustrations
Series Methods in signal transduction series
Methods in signal transduction.
Contents Electrophysiological methods for recording CRAC and TRPV5/6 channels / J. Ashot Kozak and Grigori Rychkov -- Studies of structure-function and subunit composition of orai/STIM channel / Marc Fahrner, Rainer Schindl and Christoph Romanin -- Signaling ER store depletion to plasma membrane Orai channels / Aparna Gudlur and Patrick Hogan -- Modulation of Orai1 and STIM1 by cellular factors / Jin Seok Woo, Sonal Srikanth, and Yousang Gwack -- CRAC channels and Ca2+-dependent gene expression / Yi-Chun Yeh and Anant B. Parekh -- Function of Orai/Stim proteins studied in transgenic animal models / Masatsugu Oh-Hora and Xiuyuan Lu -- Assessment of the molecular nature of STIM1/Orai1 complex by FRET / Yandong Zhou, Youjun Wang and Donald Gill -- Optogenetic approaches to control calcium entry in non-excitable cells / Lian He, Qian Zhang, Yun Huang and Yubin Zhou -- Regulation of Orai1/STIM channel activities by pH / Albert S. Yu, Zhichao Yue, Jianlin Feng and Lixia Yue -- Non-Orai partners of STIM proteins : role in ER-PM communication and Ca2+ signaling / Klaus Groschner, Niroj Shrestha and Nicola Fameli -- Store-independent Orai channels regulated by STIM / Xuexin Zhang, Maxime Gueguinou and Mohamed Trebak -- The regulation and role of store-operated Ca2+ entry in cellular proliferation / Rawad Hodeify, Fang Yu, Raphael Courjaret, Nancy Nader, Maya Dib, Lu Sun, Ethel Adap, Satanay Hubrack, and Khaled Machaca -- TRPV5 and TRPV6 calcium-selective channels / Ji-Bin Peng, Yoshiro Suzuki, Gergely Gyimesi and Matthias A. Hediger -- Determining the crystal structure of TRPV6 / Kei Saotome, Appu K. Singh and Alexander I. Sobolevsky -- Identifying TRP channel subunit stoichiometry using combined single molecule single channel determinations (SC-SMD) / Laura G Ceballos, Alexander Asanov and Luis Vaca -- Pharmacology of calcium entry channels / Gary S. Bird and James Putney Jr
Summary "Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche."--Provided by publisher
Bibliography Includes bibliographical references and index
Notes Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL
Print version record
Subject Calcium Channels -- physiology.
Calcium Signaling -- physiology.
Calcium channels -- Physiology
Cellular signal transduction.
Cellular signal transduction.
SCIENCE -- Life Sciences -- Biochemistry.
Form Electronic book
Author Kozak, Juliusz Ashot, editor.
Putney, James W., Jr, editor
ISBN 1315152592