| Description |
1 online resource (362 pages) |
| Contents |
Cover; Half Title; Title; Copyright; Contents; List of Tables and Figures; Preface; I THE DISEASE; 1. Introduction; 2. The Six Cholera Pandemics of the Nineteenth Century; 3. The Nature of the Disease; 4. The Cause of the Disease; 5. The Seventh Cholera Pandemic; II THE LONG-DELAYED DISCOVERY OF CHOLERA TOXIN; 1. The Instrument of the Disease: The Idea of Microbial Poisoning; 2. Exotoxins and Endotoxins; 3. The Quickly Discovered Toxins; Diphtheria Toxin; Tetanus Toxin; Botulinum Toxin; 4. Cholera Toxin; The Hypothesization of Cholera Toxin; Koch's Blunder; The Years in the Wilderness |
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The Revival and Extinction of DesquamationThe Animal Model; The Discovery of Cholera Toxin; III THE INTERVENTION BY THE U.S.A; 1. The Doldrums; 2. Cairo 1947: NAMRU-3 and the Beginnings of Effective Rehydration; The Origins of the NAMRUs; NAMRU-3; NAMRU-2; 3. Bangkok 1958: NAMRU-2 and the Rationalization of Rehydration; 4. Bangkok 1959: The Army and the First Civilians; The Setting; Domestic Cholera Research; The Inner Circle; The Army; The NIH; The Academics; IV THE SEATO CHOLERA RESEARCH PROGRAM AND THE PAKISTAN-SEATO CHOLERA RESEARCH LABORATORY IN DACCA; 1. The Program |
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2. Early Years at the Pakistan-SEATO Cholera Research LaboratoryV THE JOHNS HOPKINS CENTER FOR MEDICAL RESEARCH AND TRAINING IN CALCUTTA; VI LEARNING TO DEAL WITH CHOLERA; 1. Rehydration and the Problem of Acidosis and Pulmonary Oedema; 2. Tetracycline; 3. Coping with Crises; 4. Clinical Assessment of Patients; 5. El Tor Cholera; 6. Escherichia coli Diarrhoea and Other Diarrhoeas; VII THE U.S.-JAPAN COOPERATIVE MEDICAL SCIENCE PROGRAM; VIII ATTEMPTS TO PREVENT CHOLERA; 1. Antibacterial Immunization; Early Vaccine Trials; Matlab Thana Trials; 2. Antitoxic Immunization |
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The Recognition of Cholera ToxinFinkelstein's ""Choleragen; Craig's ""Skin Toxin; The Cholera Advisory Committee and Cholera Toxin; The Development of a Toxoid; Field Trials of Cholera Toxoid; 3. Does Mucin Protect Against Cholera After All?; 4. The Immunology of the Enteron, and Future Hopes; 5. Texas Star; 6. Is Immunological Protection Against Cholera Feasible or Necessary?; IX THE SIMPLE CURE OF CHOLERA AND OF OTHER INFECTIOUS DEHYDRATING DIARRHOEAL DISEASES; 1. The Normal Physiology of the Small Intestine; 2. Choleraic Morbid Physiology of the Small Intestine; 3. The Glucose Effect |
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4. Early Attempts at Oral Rehydration5. Consolidation of Oral Rehydration; 6. The Other Diarrhoeal Diseases, World-wide; X THE BIOCHEMISTRY OF CHOLERA; 1. Introduction; 2. The Release of the Second Messenger; 3. The Provision of Pure Cholera Toxin; 4. The Toxin Receptor; 5. The Molecular Structure of Cholera Toxin; 6. The Development of the Perforated Cell; 7. The Function of NAD; 8. The Present Position; XI THE INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH (ICDDR/B); 1. The Departure of R.A. Phillips; 2. The Emergence of Bangladesh; 3. The CRL; 4. The ICDDR/B |
| Notes |
The Verwey Proposal |
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Print version record |
| Form |
Electronic book
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| ISBN |
9780429704963 |
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0429704968 |
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