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Title Neurotransmitter transporters / contributors, G. Ahnert-Hilger [and others] ; editors, Harald H. Sitte and Michael Freissmuth
Published Berlin ; New York : Springer, [2006]
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Description 1 online resource (viii, 552 pages) : illustrations
Series Handbook of experimental pharmacology, 0171-2004 ; v. 175
Handbook of experimental pharmacology ; v. 175
Contents Zn2+ Modulation of Neurotransmitter Transporters -- Molecular Microfluorometry: Converting Arbitrary Fluorescence Units into Absolute Molecular Concentrations to Study Binding Kinetics and Stoichiometry in Transporters -- Structure/Function Relationships in Serotonin Transporter: New Insights from the Structure of a Bacterial Transporter -- The Importance of Company: Na+ and Cl? Influence Substrate Interaction with SLC6 Transporters and Other Proteins -- Currents in Neurotransmitter Transporters -- Mutational Analysis of Glutamate Transporters -- The Diverse Roles of Vesicular Glutamate Transporter 3 -- Extraneuronal Monoamine Transporter and Organic Cation Transporters 1 and 2: A Review of Transport Efficiency -- The Role of SNARE Proteins in Trafficking and Function of Neurotransmitter Transporters -- Regulation of the Dopamine Transporter by Phosphorylation -- The Dopamine Transporter: A Vigilant Border Control for Psychostimulant Action -- Oligomerization of Neurotransmitter Transporters: A Ticket from the Endoplasmic Reticulum to the Plasma Membrane -- Acute Regulation of Sodium-Dependent Glutamate Transporters: A Focus on Constitutive and Regulated Trafficking -- Regulation and Dysregulation of Glutamate Transporters -- Regulation of Vesicular Monoamine and Glutamate Transporters by Vesicle-Associated Trimeric G Proteins: New Jobs for Long-Known Signal Transduction Molecules -- Human Genetics and Pharmacology of Neurotransmitter Transporters -- ADHD and the Dopamine Transporter: Are There Reasons to Pay Attention? -- Inactivation of 5HT Transport in Mice: Modeling Altered 5HT Homeostasis Implicated in Emotional Dysfunction, Affective Disorders, and Somatic Syndromes -- Lessons from the Knocked-Out Glycine Transporters -- The Norepinephrine Transporter in Physiology and Disease -- The High-Affinity Choline Transporter: A Critical Protein for Sustaining Cholinergic Signaling as Revealed in Studies of Genetically Altered Mice
Summary Gives a survey of the status of the structure, function, regulation and molecular pharmacology of Neurotransmitter Transporters. This book aims to serve as both, a useful compendium of concepts and an inspiring starting point
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record
In Springer e-books
Subject Carrier proteins.
Neurotransmitter Agents.
Carrier Proteins.
Form Electronic book
Author Ahnert-Hilger, G. (Gudrun)
Freissmuth, Michael.
Sitte, Harald H.
ISBN 3540297839 (Cloth)
9783540297833 (Cloth)