Title Quadruplex nucleic acids / Jonathan B. Chaires, David Graves, editors ; with contributions by R. Buscaglia [and others]

Published Berlin : Springer, ©2013

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Description 1 online resource (x, 278 pages) : illustrations (some color) Series Topics in current chemistry, 1436-5049 ; 330 Topics in current chemistry ; 330 Contents Gaining Insights into the Small Molecule Targeting of the G-Quadruplex in the c-MYC Promoter Using NMR and an Allele-Specific Transcriptional Assay / Christine E. Kaiser, Vijay Gokhale, Danzhou Yang -- Higher-Order Quadruplex Structures / Luigi Petraccone -- Investigation of Quadruplex Structure Under Physiological Conditions Using In-Cell NMR / Robert Hänsel, Silvie Foldynová-Trantírková, Volker Dötsch -- Circular Dichroism of Quadruplex Structures / Antonio Randazzo, Gian Piero Spada, Mateus Webba da Silva -- Molecular Crowding and Hydration Regulating of G-Quadruplex Formation / Daisuke Miyoshi, Takeshi Fujimoto, Naoki Sugimoto -- Visualizing the Quadruplex: From Fluorescent Ligands to Light-Up Probes / Eric Largy, Anton Granzhan, Florian Hamon, Daniela Verga -- Calculation of Hydrodynamic Properties for G-Quadruplex Nucleic Acid Structures from in silico Bead Models / Huy T. Le, Robert Buscaglia, William L. Dean -- Energetics of Ligand Binding to G-Quadruplexes / Concetta Giancola, Bruno Pagano -- Tetramolecular Quadruplex Stability and Assembly / Phong Lan Thao Tran, Anne De Cian, Julien Gros, Rui Moriyama Summary Gaining Insights into the Small Molecule Targeting of the G-Quadruplex in the c-MYC Promoter Using NMR and an Allele-Specific Transcriptional Assay, by Christine E. Kaiser, Vijay Gokhale, Danzhou Yang and Laurence H. Hurley.- Higher-Order Quadruplex Structures, by Luigi Petraccone.- Investigation of Quadruplex Structure Under Physiological Conditions Using In-Cell NMR, by Robert Hänsel, Silvie Foldynová-Trantírková, Volker Dötsch and Lukás Trantírek.- Circular Dichroism of Quadruplex Structures, by Antonio Randazzo, Gian Piero Spada and Mateus Webba da Silva.- Molecular Crowding and Hydration Regulating of G-Quadruplex Formation, by Daisuke Miyoshi, Takeshi Fujimoto and Naoki Sugimoto.- Visualizing the Quadruplex: From Fluorescent Ligands to Light-Up Probes, by Eric Largy, Anton Granzhan, Florian Hamon, Daniela Verga and Marie-Paule Teulade-Fichou.- Calculation of Hydrodynamic Properties for G-Quadruplex Nucleic Acid Structures from in silico Bead Models, by Huy T. Le, Robert Buscaglia, William L. Dean, Jonathan B. Chaires and John O. Trent.- Energetics of Ligand Binding to G-Quadruplexes, Concetta Giancola and Bruno Pagano.- Tetramolecular Quadruplex Stability and Assembly, by Phong Lan Thao Tran, Anne De Cian, Julien Gros, Rui Moriyama and Jean-Louis Mergny Bibliography Includes bibliographical references and index Notes English Online resource; title from PDF title page (SpringerLink, viewed February 25, 2013) Subject Quadruplex nucleic acids. Chimie. Science des matériaux. Quadruplex nucleic acids Form Electronic book Author Chaires, Jonathan B Graves, David Buscaglia, R. (Robert) ISBN 9783642347436 3642347436

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