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E-book

Title Management of periprosthetic joint infections (PJIs) / edited by J.J. Chris Arts and Jan Geurts
Published Duxford, United Kingdom : Woodhead Publishing, 2016, ©2017

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Description 1 online resource
Series Woodhead Publishing series in biomaterials
Woodhead Publishing series in biomaterials.
Contents Front Cover; Management of Periprosthetic Joint Infections (PJIs); Copyright; Contents; List of contributors; Preface; Part One: Fundamentals of periprosthetic joint infections; Chapter 1: Prevention of joint infections; 1.1 Introduction; 1.2 Preoperative considerations; 1.2.1 Preoperative patient selection and risk factors for infection; 1.2.2 Nonmodifiable comorbidities; 1.2.3 Modifiable comorbidities; 1.2.3.1 Active pyogenic infections; 1.2.3.2 Colonization with Staphylococcus aureus; 1.2.3.3 Hyperglycemia and diabetes; 1.2.3.4 Dental disease
1.2.3.5 Immunosuppression and autoimmune/rheumatologic disease1.2.3.6 Human immunodeficiency virus (HIV); 1.2.3.7 Obesity and malnutrition; 1.2.3.8 Integumentary alterations; 1.2.3.9 Tobacco, Ethanol, and intravenous drug use; 1.2.3.10 Preoperative urinary screening and management of bacteriuria; 1.3 Prevention of infection in the perioperative period; 1.3.1 Body cleansing at home in anticipation of surgery; 1.3.2 Preoperative hair management; 1.3.3 Perioperative antibiotics; 1.3.4 Surgical skin preparation
1.3.5 Antibiotic-loaded bone cement (ALBC) prophylaxis in primary and revision arthroplasty1.3.6 The role of laminar air flow and body suits in operating rooms during arthroplasty; 1.4 Prevention of infection after arthroplasty; 1.4.1 Early postoperative period; 1.4.1.1 Wound issues; 1.4.1.2 Cellulitis and superficial wound infection; 1.4.1.3 Postoperative fever; 1.4.2 Late considerations; 1.5 Conclusions and future trends; References; Chapter 2: Biofilm formation and the biological response; 2.1 Introduction; 2.2 Biofilm formation; 2.2.1 Matrix proteins
2.2.1.1 Biofilm-associated protein (Bap)2.2.1.2 Outer membrane vesicles (OMVs); 2.2.1.3 Bacterial nucleoid-binding proteins; 2.3 Resistance to antimicrobial agents; 2.3.1 Delayed penetration of the antimicrobial agent; 2.3.2 Altered growth rate of biofilm organisms; 2.4 Host response against biofilm; 2.4.1 How biofilm evades host' defenses; 2.5 Clinical significance of biofilm; 2.6 Therapeutic strategies against biofilm; 2.6.1 Biofilm matrix-degrading enzymes; 2.6.2 Ultrasonic treatment; 2.6.3 Bacteriophages; 2.6.4 Quorum sensing inhibitors; 2.6.5 Silver nanoparticles; 2.7 Future trends
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Artificial joints -- Infections
Artificial joints -- Complications
MEDICAL -- Surgery -- General.
Form Electronic book
Author Arts, J. J. Chris
Geurts, Jan
ISBN 0081002424
9780081002421