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Author Snelling, Hayley

Title Identification of genes in the liver of Psammomys obesus associated with Type II diabetes / by Hayley Snelling
Published [Place of publication not identified] : [publisher not identified], 2000


Location Call no. Vol. Availability
 W'PONDS  616.462 Sne/Iog  AVAILABLE
Description [ix], 131 leaves ; 30 cm
Summary Type II diabetes is characterised by hyperglycemia and disturbances of fat, carbohydrate and protein metabolism. It occurs mainly in adults, with obesity being the most modifiable risk factor. This project utilised the Israeli Sand Rat (Psammomys obesus) and some of the latest molecular biology technology including differential display, membrane microarray and real-time PCR to detect genes in the liver that may be associated with the development of Type II diabetes and/or obesity. This study showed calpain, a proteolytic inhibitor and calpastatin, its natural inhibitor to be disregulated in the liver during the diabetic state
Notes Submitted to the School of Health Sciences of the Faculty of Health and Behavioural Sciences, Deakin University
Thesis (M.Sc.)--Deakin University, Victoria, 2000
Bibliography Bibliography: leaves 111-131
Subject Non-insulin-dependent diabetes -- Pathogenesis.
Obesity -- Pathophysiology.
Gene expression.
Genre/Form Academic theses.
Author Deakin University. Faculty of Health and Behavioural Sciences
Deakin University. School of Health Sciences