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Title Recombination and meiosis : models, means, and evolution / volume editors, Richard Egel, Dirk-Henner Lankenau
Published Berlin ; New York : Springer, [2008]
©2008
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Description 1 online resource (xix, 390 pages) : illustrations
Series Genome dynamics and stability, 1861-3373 ; 3
Genome dynamics and stability ; 3. 1861-3373
Contents Evolution of Models of Homologous Recombination / James E. Haber -- Searching for Homology by Filaments of RecA-Like Proteins / Chantal Prévost -- Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates / Kirk T. Ehmsen, Wolf-Dietrich Heyer -- Meiotic Chromatin: The Substrate for Recombination Initiation / Michael Lichten -- Meiotic Recombination in Schizosaccharomyces pombe: A Paradigm for Genetic and Molecular Analysis / Gareth Cromie, Gerald R. Smith -- Nuclear Movement Enforcing Chromosome Alignment in Fission Yeast -- Meiosis Without Homolog Synapsis / Da-Qiao Ding, Yasushi Hiraoka -- On the Origin of Meiosis in Eukaryotic Evolution: Coevolution of Meiosis and Mitosis from Feeble Beginnings / Richard Egel, David Penny -- The Legacy of the Germ Line -- Maintaining Sex and Life in Metazoans: Cognitive Roots of the Concept of Hierarchical Selection / Dirk-Henner Lankenau -- Lessons to Learn from Ancient Asexuals / Isa Schon, Dunja K. Lamatsch, Koen Martens
Summary Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II - reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm - in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillar
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Genetic recombination.
Meiosis.
Recombination, Genetic.
Meiosis.
Models, Molecular.
Nondisjunction, Genetic.
Schizosaccharomyces -- genetics.
Form Electronic book
Author Egel, Richard, 1942-
Lankenau, Dirk-Henner.
ISBN 3540689834 (alk. paper)
3540689842
9783540689836 (alk. paper)
9783540689843