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Book Cover
Streaming video
Author Von Kalle, Christof, (National Center for Tumor Diseases and German Cancer Research Center, Germany), speaker

Title Tracking vector insertion sites to explore the biology of transduced cells in vivo / Christof Von Kalle
Published London : Henry Stewart Talks, 2014
Online access available from:
HSTalks Biomedical & Life Sciences Collection    View Resource Record  


Description 1 online resource (1 streaming video file (35 min.) : color, sound)
Series Gene transfer and gene therapy, 2056-452X
Henry Stewart talks. Biomedical & life sciences collection. Gene transfer and gene therapy
Contents Contents: Clonal marking by integrating vectors -- Integration site analysis by LAM-PCR -- Analysis of gene therapy clinical trials for X-SCID, X-CGD, ADA-SCID & Cancer -- Avoiding oncogenesis in gene therapy -- Gene therapy for Wiskott-Aldrich Syndrome (WAS) -- Characterization & understanding of pathogenesis -- Integrations in known proto-oncogenes -- Possible triggers of AML development -- Safer vector systems & new technologies -- Lentiviral SIN-vectors -- Influence of vector type on clinical outcome -- LV integration site analysis: X-ALD trial -- Repopulation of hematopoietic system -- Targeted genome modification: nucleases -- Specificity of DNA modification by ZFN -- The TALEN nuclease and how it performs
Notes Animated audio-visual presentation with synchronized narration
Title from title frames
Mode of access: World Wide Web
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
Subject Gene therapy.
Genetic transformation.
Genetic vectors.
Medical genetics.
Genetic Therapy -- methods.
Genetic Vectors -- genetics.
Hematopoietic System.
Lentivirus -- genetics.
Severe Combined Immunodeficiency.
Virus Integration -- genetics.
Wiskott-Aldrich Syndrome -- therapy.
X-Linked Combined Immunodeficiency Diseases.
Genre/Form Video recordings.
Form Streaming video