| Description |
1 online resource |
| Contents |
Front Cover -- MINERALIZING VESICLES -- MINERALIZING VESICLES: From Biochemical and Biophysical Properties to Their Roles in Physiology and Disease -- Copyright -- Contents -- List of contributors -- Biographies -- Preface -- 1 -- General aspects of extracellular vesicles in bone formation and remodeling -- 1. Introduction -- 2. Communications between bone cells -- 3. Extracellular vesicles -- 4. Bone cell overview -- 5. Bone marrow cells interacting with skeletal cells -- 6. Extracellular vesicle trafficking in the bone microenvironment -- 6.1 Extracellular vesicles and osteoblasts |
|
6.2 Extracellular vesicles and osteocytes -- 6.3 Extracellular vesicles and osteoclasts -- 7. Extracellular vesicles in fracture healing -- 8. Extracellular vesicles and bone cancer -- 9. Medical applications -- 10. Conclusions -- List of abbreviations -- Acknowledgments -- References -- 2 -- Physiological biomineralization. The properties and role of matrix vesicles in skeletal and dental calcifications -- 1. Introduction -- 2. Biomineralization in teeth -- 3. Biomineralization in bones -- 4. Determinants of mineralization support the functions of matrix vesicles -- 4.1 Matrix vesicles in dentin |
|
4.2 Matrix vesicles in cartilage -- 4.3 Matrix vesicles in bones -- 5. Conclusions -- List of abbreviations -- Acknowledgments -- References -- 3 -- Pathological biomineralization. Part I: Mineralizing extracellular vesicles in cardiovascular diseases -- 1. Introduction -- 2. Extracellular vesicles: origin and classification -- 3. Extracellular vesicles related to cardiovascular diseases -- 3.1 Extracellular vesicles released from vascular smooth muscle cells -- 3.2 Extracellular vesicles released from M1 macrophages -- 4. Extracellular vesicles: biomarkers of cardiovascular diseases |
|
4.1 Extracellular vesicles carrying RNAs -- 4.2 Extracellular vesicles carrying proteins -- 4.3 Extracellular vesicles carrying lipids and metabolites -- 5. Extracellular vesicles as drug delivery vehicles in cardiovascular disease -- 6. Conclusions -- List of abbreviations -- Acknowledgments -- References -- 4 -- Pathologic biomineralization: part II: mineralizing extracellular vesicles in osteoarthritis -- 1. Introduction -- 2. Historical perspective -- 3. Characterization of ACVs -- 3.1 ACV isolation procedures -- 3.2 ACV mineralization assays -- 3.3 ACV contents |
|
4. ACVs from osteoarthritis cartilage -- 4.1 Differences in ACVs in osteoarthritis and normal cartilage -- 4.2 Mechanisms of vesicle formation -- 5. Factors affecting ACV mineralization -- 5.1 Pi/PPi ratio -- 5.2 Extracellular matrix composition -- 5.3 Drugs -- 6. Conclusions and future directions -- List of abbreviations -- References -- 5 -- The biochemistry of mineralizing extracellular vesicles. Part I: The role of phosphatases -- 1. Inorganic phosphate (Pi) and pyrophosphate (PPi): a physicochemical balance -- 2. The molecules regulating the Pi/PPi ratio |
| Notes |
Print version record |
| Subject |
Cell organelles.
|
| Form |
Electronic book
|
| Author |
Bottini, Massimo
|
|
Ramos, Ana Paula
|
| ISBN |
0323991599 |
|
9780323991599 |
|
