| Description |
1 online resource (2 v. (xix, 3278 pages)) : illustrations (some color) |
| Contents |
V. 1. I. Epithelial and nonepithelial transport and regulation. Epithelial cell structure and polarity / Karl S. Matlin and Michael J. Caplan -- Mechanisms of ion transport across cell membranes / Luis Reuss and Guillermo A. Altenberg -- Renal ion-translocating ATPases / Dominique Eladari, Udo Hasler and Eric Féraille -- Mechanisms of water transport across cell membranes and epithelia / Guillermo a. altenberg and Luis Reuss -- Cell volume control / Florian Lang -- Solute transport, energy consumption, and production in the kidney / Takashi Sekine and Hitoshi Endou -- Electrophysiological analysis of transepithelial transport / Henry Sackin and Lawrence G. Palmer -- Renal ion channels, electrophysiology of transport, and channelopathies / James D. Stockand -- Microvascular permeability and the exchange of water and solutes across microvascular walls / C. Charles Michel -- External balance of electrolytes and acids and alkali / Man S. Oh -- Renal cilia structure, function, and physiology / Jay N. Pieczynski and Bradley K. Yoder -- Intercellular junctions / Alan S.L. Yu, Fiona Hanner and János Peti-Peterdi -- Principles of cell signaling / Lloyd Cantley -- Scaffolding proteins in transport regulation / Paul A. Welling --The renin-angiotensin system / Thu H. Le ... [et al.] -- Neural control of renal function / Edward J. Johns and Ulla C. Kopp -- Eicosanoids and renal function / Matthew D. Breyer, Raymond C. Harris and Richard M. Breyer -- Extracellular nucleotides and renal function / David G. Shirley ... [et al.] -- Paracrine regulation of renal function by dopamine / Pedro A. Jose, Robin A. Felder and Gilbert M. Eisner -- II. Structural and functional organization of the kidney. Structural organization of the mammalian kidney / Wilhelm Kriz and Brigitte Kaissling -- Biophysical basis of glomerular filtration / Scott C. Thomson and Roland C. Blantz -- Glomerular cell biology / Yoshiro Maezawa, Davide Cina and Susan E. Quaggin -- Function of the juxtaglomerular apparatus: control of glomerular hemodynamics and renin secretion / Jürgen B. Schnermann and Hayo Castrop -- Renal cortical and medullary microcirculations: structure and function / Thomas L. Pallone and Chunhua Cao -- Molecular and cellular mechanisms of kidney development / Kevin T. Bush, Hiroyuki Sakurai and Sanjay K. Nigam -- Molecular and cellular mechanisms of glomerular capillary development / Jeffrey H. Miner and Dale R. Abrahamson --Postnatal renal development / Michel Baum, Jyothsna Gattineni and Lisa M. Satlin -- Renal hyperplasia and hypertrophy / Paul T. Brinkkoetter, Sian V. Griffin and Stuart J. Shankland -- Stem cells and generation of new cells in the adult kidney / Juan A. Oliver and Qais Al-Awqati -- III. Fluid and electrolyte regulation and dysregulation. Epithelial Na+ channels / Shaohu Sheno, Kenneth R. Hallows and Thomas R. Kleyman -- Anion channels / Owen M. Woodward and William B. Guggino -- Physiology and pathophysiology of the NaCl co-transporters in the kidney / Gerardo Gamba -- Sodium and chloride transport: proximal nephron / Alan M. Weinstein -- Sodium chloride transport in the loop of Henle, distal convoluted tubule, and collecting duct / Gerardo Gamba, Wenhui Wang and Laurent Schild -- Mineralocorticoid action in the aldosterone sensitive distal nephron / Oliver Staub and Johannes Loffing -- Inherited disorders of renal salt homeostasis: insights from molecular genetics studies / Ute I. Scholl and Richard P. Lifton -- |
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Natriuretic hormones / David L. Vesely -- Pathophysiology of sodium retentiona nd wastage / Biff F. Palmer, Robert J. Alpern and Donald W. Seldin --Physiology and pathophysiology of hypertension / John E. Hall, Joey P. Granger and Michael E. Hall -- Physiology and pathophysiology of diuretic action / David H. Ellison -- Aquaporin water channels in mammalian kidney / Søren Nielsen ... [et al.] -- Thirst and vasopressin / Gary L. Robertson -- The urine concentrating mechanism and urea transporters / Jeff M. Sands and Harold E. Layton -- Hyponatremia / Richard H. Sterns, Stephen M. Silver and J. Kevin Hix -- Hypernatremic states / Christopher J. Rivard, Wei Wang and Laurence Chan -- Polyuria and diabetes insipidus / Daniel G. Bichet -- The molecular biology of renal K+ channels / Wenhui Wang and Chou-Long Huang -- Extrarenal potassium metabolism / Vaibhav Sahni, Aleksandra Gmurczyk and Robert M. Rosa -- Regulation of K+ excretion / Gerhard Malnic ... [et al.] -- Physiopathology of potassium deficiency / Francesco Trepiccione, Miriam Zacchia and Giovambattista Capasso -- V. 2. Clinical disorders of hyperkalemia / Kamel S. Kamel ... [et al.] -- Control of intracellular pH / Mark O. Bevensee and Walter F. Boron -- SLC4 sodium-driven bicarbonate transporters / Ira Kurtz -- The SLC4 anion exchanger gene family / Andrew K. Stewart and Seth L. Alper --Cellular mechanisms of renal tubular acidification / L. Lee Hamm, Robert J. alpern and Patricia A. Preisig -- Chemoreceptors, breathing and pH / Eugene Nattie -- Renal ammonium ion production and excretion / Norman P. Curthoys -- Clinical syndromes of metabolic alkalosis / Orson W. Moe, Robert J. Alpern and Donald W. Seldin -- Clinical syndromes of metabolic acidosis / Reto Krapf, Donald W. Seldin and Robert J. Alpern -- Respiratory acid-base disorders / Nicolaos E. Madias and Horacio J. Adrogue -- Mechanisms and disorders of magnesium metabolism / Karl P. Schlingmann, Gary A. Quamme and Martin Konrad -- Calcium channels / Joost G.J. Hoenderop and René J.M. Bindels -- The calcium-sensing receptor / Edward M. Brown ... [et al.] -- Renal calcium metabolism / José F. Bernardo and Peter A. Friedman -- The hormonal regulation of calcium metabolism / Peter J. Tebben and Rajiv Kumar -- Disorders of calcium metabolism / Cristina Dumitru and John Wysolmerski -- Pathogenesis and treatment of nephrolithiasis / Fredric L. Coe, Andrew Evan and Elaine Worcester -- Proximal tubular handling of phosphate / Heini Murer ... [et al.] -- Clinical disturbances of phosphate homeostasis / Theresa J. Berndt and Rajiv Kumar --Glucose reabsorption in the kidney / Charles S. Hummel and Ernest M. Wright -- Kidney transport of amino acids and oligopeptides, and aminoacidurias / Simone M.R. Camargo ... [et al.] -- Organic anion and cation transporters in renal elimination of drugs / Gerhard Burckhardt and Hermann Koepsell -- Renal filtration, transport, and metabolism of albumin and albuminuria / Erik Ilsø Christensen, Rikke Nielsen and Henrik Birn -- |
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IV. Pathophysiology of renal disease. Physiologic principles in the clinical evaluation of electrolyte, water, and acid-base disorders / Daniel Batlle, Sheldon Chen and Syed K. Haque -- Biomarkers for assessment of renal function during acute kidney injury / Prasad Devarajan -- Pathophysiology of acute kidney injury / Bruce A. Molitoris and Asif Sharfuddin -- Ischemic renal disease / Christopher J. Cooper, Lance D. Dworkin and William L. Henrich -- Pathophysiology and pathogenesis of diabetic neophropathy / sheldon Chen, Charbel Khoury and Ruad N. Ziyadeh -- Renal failure in cirrhosis / Peter Ginés, Andrés Cárdenas and Robert W. Schrier -- Autosomal docimant polycystic kidney disease / Stefan Somlo, Vincente E. Torres and Michael J. Caplan -- Renal physiology and disease in pregnancy / Marshall D. Lindheimer, Kirk P. Conrad and S. Ananth Karumanchi -- Immune and inflammatory glomerular diseases / Anup Manoharon ... [et al.] -- Immunologic mechanisms of vasculitis / Jonathon W. Homeister, J. Charles Jennette and Ronald J. Falk -- Genetic abnormalities in glomerular function / Yoav Segal and Clifford E. Kashtan -- Celllar mechanisms of drug nephrotoxicity / Robert James Walker and Zoltán Huba Endre -- Role of glomerular mechanical stress in the pathogenesis of chronic kidney disease / Clarice Kazue Fujihara and Roberto Zatz -- Role of proteinuria in the progression of renal disease / Mauro Abbate ... [et al.] -- The inflammatory response to ischemic acute renal injury / Christopher Y. Lu -- Catalytic (labile) iron in kidney disease / Mohan Rajapurkar, Radhakrishna Baliga and Sudhir V. Shah -- Chronic kidney disease: pathophysiology and the influence of dietary protein / Biruh T. Workeneh and William E. Mitch -- Management of calcium and bone disease in renal patients / L. Darryl Quarles -- Hematopoiesis and the kidney / Armin Kurtz, Roland H. Wenger and Kai-Uwe Eckardt -- Individualizing the dialysate to address electrolyte disturbances in the dialysis patinet / Biff F. Palmer -- Homeostasis of solute and water by the transplanted kidney / J. Harold Helderman ... [et al.] -- Renal disposition of drugs and translation to dosing strategies / Pär Matsson, Kathleen M. Giacomini and D. Craig Brater |
| Summary |
A classic nephrology reference for over 25 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information. Offers the most comprehensive coverage on the market of fluid and electrolyte regulation and dysregulation in 85 completely revised chapters and 10 new chapters.Includes 4sections, 62 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Includes foreword by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology and editors of the previous three editions |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Description based on online resource; title from electronic title page (ebrary, viewed on June 3, 2015) |
| Subject |
Kidneys -- Physiology
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Kidneys -- Pathophysiology
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Kidneys -- Diseases.
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Kidney -- physiology
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Kidney Diseases -- physiopathology
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Kidney Diseases
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Kidneys -- Diseases
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Kidneys -- Pathophysiology
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Kidneys -- Physiology
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| Form |
Electronic book
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| Author |
Alpern, Robert J., editor.
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Moe, Orson W., editor.
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Caplan, Michael, editor.
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