| Description |
1 online resource (xv, 1194 pages) : illustrations (chiefly color) |
| Series |
Cambridge medicine |
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Cambridge medicine (Series)
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| Contents |
Section 1. Principles of drug action -- 1. Pharmacodynamic principles of drug action / Stuart A. Forman -- 2. G-protein-coupled receptors / Marcel E. Durieux -- 3. Ion channels / Thomas McDowell, Misha Perouansky, and Robert A. Pearce -- 4. Other signaling pathways / Istvan Nagy, Isobel Lever, and Mario Cibelli -- 5. Principles of pharmacokinetics / Thomas W. Schnider and Charles F. Minto -- 6. Principles of drug biotransformation / Evan D. Kharasch -- 7. Drug transport and transporters / Roland J. Bainton and Evan D. Kharasch -- 8. Target-controlled infusions and closed-loop administration / Michel M.R.F. Struys and Tom De Smet -- 9. Alternative routes of drug administration / Ola Dale -- 10. Principles of pharmacogenetics / Kirk Hogan -- 11. Pharmacodynamic drug interactions in anesthesia / Talmage D. Egan and Charles F. Minto -- 12. Pharmacoeconomics / Alex Macario |
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Section 2. Physiologic substrates of drug action / 13 Sleep and consciousness -- George A. Mashour and Max Kelz -- 14. Synaptic transmission / M.B. MacIver -- 15. Memory, learning, and cognition / Robert A. Veselis -- 16. Mechanisms of pain transmission and transduction / Robert W. Gereau IV and Laura F. Cavallone -- 17. The generation and propagation of action potentials / Gary R. Strichartz -- 18. Neuromuscular function / Joe Henry Steinbach and Ling-Gang Wu -- 19. Vascular reactivity / Isao Tsuneyoshi, Josephine M. Garcia-Ferrer, Hung Pin Liu, and Walter A. Boyle -- 20. Cardiac rhythm / Brian S. Donahue and Jeffrey R. Balser -- 21. Myocardial performance / Pierre Foëx and Helen Higham -- 22. Autonomic function / Jonathan Moss and David Glick -- 23. Immunity and inflammation / Nigel R. Webster and Helen F. Galley |
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Section 3. Essential drugs in anesthetic practice -- 24. Mechanisms of anesthetic action / C. Michael Crowder and Alex S. Evers -- 25. Pharmacokinetics of inhaled anesthetics / Geoff Lockwood -- 26. Clinical pharmacology of inhaled anesthetics / Thomas J. Ebert and Larry Lindenbaum -- 27. Pharmacokinetics of intravenous anesthetics / Frédérique S. Servin and John W. Sear -- 28. Clinical pharmacology of intravenous anesthetics / John W. Sear -- 29. Benzodiazepines / Uwe Rudolph, M. Frances Davies, and Juliana Barr -- 30. Alpha2-agonists and other sedatives and amnestics / Robert D. Sanders and Mervyn Maze -- 31. Mechanisms of action of opioids / Michael Schäfer -- 32. Pharmacokinetics of opioids / Dhanesh K. Gupta, Tom C. Krejcie, and Michael J. Avram -- 33. Clinical pharmacology of opioids / Carl E. Rosow and Mark Dershwitz -- 34. Nonsteroidal anti-inflammatory drugs / Nilesh Randive and Richard M. Langford -- 35. Other ion-channel and receptor ligands for analgesia / Mark A. Schumacher and Helge Eilers -- 36. Local anesthetics / Francis V. Salinas and David B. Auyong -- 37. Antiepileptic and antipsychotic drugs / W. Andrew Kofke -- 38. Neuromuscular blocking drugs / Heidrun Fink, Manfred Blobner, and J.A. Jeevendra Martyn -- 39. Drugs for reversal of neuromuscular blockade / Mohamed Naguib -- 40. Sympathomimetic and sympatholytic drugs / David F. Stowe and Thomas J. Ebert -- 41. Parasympathomimetic and parasympatholytic drugs / Berend Mets and Imre Redai -- 42. Beta-blockers and other adrenoceptor antagonists / Andrew J. Patterson -- 43. Antiarrhythmic drugs / Aman Mahajan and Charles W. Hogue Jr. -- 44. Positive inotropic drugs / Paul S. Pagel and David C. Warltier -- 45. Vasodilators / Roger A. Johns and Stephen Yang -- 46. Calcium channel blockers / W. Scott Beattie -- 47. Bronchodilators / Charles W. Emala -- 48. Pulmonary vasodilators / Sunita Sastry and Ronald G. Pearl -- 49. Renal protection and pharmacology / Dean R. Jones and H.T. Lee -- 50. Fluids and electrolytes / Robert G. Hahn -- 51. Corticosteroids and anti-inflammatory drugs / Clifford S. Deutschman -- 52. Antirejection drugs and immunosuppressants / Nándor Marczin and Kristof Racz -- 53. Antimotility and antisecretory drugs / Robert P. Walt and Eugene B. Campbell -- 54. Antiemetics / Jens Scholz, Markus Steinfath, and Patrick Meybohm -- 55. Insulin and antihyperglycemic drugs / Nick Oliver, Martin Smith, and Stephen Robinson -- 56. Nutritional pharmacology / Paul Wischmeyer -- 57. Drugs affecting coagulation and platelet function / Troy Wildes, Michael Avidan, and George Despotis -- 58. Obstetric pharmacology / Tony Gin -- 59. Antimicrobial therapy / Conan MacDougall, B. Joseph Guglielmo, and Jeanine Wiener-Kronish |
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Section 4. Clinical applications: evidence-based anesthesia practice -- 60. Preoperative drug management / Laureen Hill -- 61. Induction of anesthesia / T. Andrew Bowdle -- 62. Maintenance of and emergence from anesthesia / J. Lance Lichtor -- 63. Management of sedation, analgesia, and delirium / Christopher G. Hughes, Stuart McGrane, E. Wesley Ely, and Pratik P. Pandaharipande -- 64. Postoperative analgesia / Richard W. Rosenquist and Ellen W. King -- 65. Control of blood pressure and vascular tone / Arthur Wallace -- 66. Cardiac protection and pharmacologic management of myocardial ischemia / Eric Jacobsohn, Waiel Almoustadi, and Chinniampalayam Rajamohan -- 67. Management of patients with chronic alcohol or drug use / Howard B. Gutstein -- 68. Drug allergy and treatment / Jerrold H. Levy -- 69. Pediatric pharmacology / Greg B. Hammer and Brian J. Anderson -- 70. Geriatric pharmacology / Jeffrey H. Silverstein -- 71. Emerging concepts of anesthetic neuroprotection and neurotoxicity / Brian P. Head and Piyush Patel |
| Summary |
"In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, second edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period"--Provided by publisher |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource and print version record |
| Subject |
Anesthetics.
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Anesthetics -- pharmacology.
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Analgesics -- pharmacology.
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| Form |
Electronic book
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| Author |
Evers, Alex S., editor
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Kharasch, Evan D., editor
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Maze, M. (Mervyn), editor
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| ISBN |
0511781938 (electronic bk.) |
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1139099248 (electronic bk.) |
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1139100602 |
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9780511781933 (electronic bk.) |
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9781139099240 (electronic bk.) |
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9781139100601 |
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(hardback) |
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(print) |
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(hardback) |
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(print) |
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