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E-book

Title Botanical leads for drug discovery / Bikarma Singh, editor
Published Singapore : Springer, 2020
©2020

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Description 1 online resource (xxvi, 468 pages)
Contents Plant-Derived Drug Discovery: Introduction to Recent Approaches / Bharat Goel, Bharat Sahu, Shreyans Kumar Jain -- Herbal Medicines as a Rational Alternative for Treatment of Human Diseases / Anand Kumar Chaudhari, Somenath Das, Bijendra Kumar Singh, Jitendra Prasad, Nawal Kishore Dubey, Abhishek Kumar Dwivedy -- Effect of Natural Products on Improvement of Blood Pathophysiology for Management of Sickle Cell Anemia / Abhishek Gour, Ashish Dogra, Shipra Bhatt, Utpal Nandi -- Anti-inflammatory Activity of Medicinal Plants: Present Status and Future Perspectives / Sonam Chouhan, Sanjay Guleria -- Cannabinoids as Promising Anti-inflammatory Agent / Nagma Banjare, Bhushan S. Bhale, Prem N. Gupta -- Plant Volatile Organic Compounds and Neuroregenerative Health / Rekha Chouhan, Sajad Ahmed, Sumit G. Gandhi -- Medicinal Plants and Their Role in Inflammation: A Close Look on Future Drug Discovery / Gifty Sawhney, Satinder Kaur, Asha Bhagat, Zabeer Ahmed -- Phytochemistry and Pharmacological Activities of Rhodiola imbricata Edgew., a High Value Medicinal Herb of Cold Desert Himalaya / Venugopal Singamaneni, Upasana Sharma, Bashir Lone, Prasoon Gupta -- Phyllanthus amarus Schum. and Thonn. as Herbal Medicine: Ethnobotany, Phytochemistry, and Pharmacology Aspects / Sunil Kumar -- Medicinal Applications of Cannabidiol from the Genus Cannabis L. / Debojyoti Bag, Aliya Tabassum, Nidhi Arora, Praveen Kumar Verma, Sanghapal D. Sawant -- Genetic Variability in Ocimum L. Germplasm: Medicinal and Economic Potential for Value Addition and Product Development / Smita Singh, Raj Kishori Lal, Bikarma Singh -- Chemical Constituents and Pharmacological Activities of Marrubium vulgare L., an Important Medicinal Herb / Shabir A. Dar, Anil Bhushan, Prasoon Gupta -- Ethnobotany as a Science of Preserving Traditional Knowledge: Traditional Uses of Wild Medicinal Plants from District Reasi, J & K (Northwestern Himalaya), India / Shiekh Marifatul Haq, Bikarma Singh -- Medicinal Value of High-Altitude Plants of Indian Himalaya / Jaspreet Kour, Shilpi Balgotra, Palvi Rajput, Harpreet Kour, Praveen Kumar Verma, Sanghapal D. Sawant -- Medicinal Plants of District Kupwara Used in the Treatment of Human Diseases and Their Associated Biological Functions / Mudasir Nazir Bhat, Bikarma Singh, Mohammed Asif Chowdhary, Sumit Singh, Opender Surmal, Rajendra Bhanwaria et al. -- Capsicum chinense Jacq.: Ethnobotany, Bioactivity and Future Prospects / Joyashree Baruah, Mohan Lal -- Indigenous Plant Knowledge for Human Health Care from Jasrota Wildlife Sanctuary (Western Himalaya), India / Bishander Singh, Anand Kishor, Bikarma Singh -- Ethanobotany and Phytochemistry of Lantana camara L. (Verbenaceae) / Bishander Singh, Anand Kishor, Bikarma Singh -- Cymbopogon winterianus Jowitt ex Bor, a Hub for Various Industrial and Pharmaceutical Applications / Sunita Munda, Mohan Lal -- Botanical Sources, Chemistry Aspects and Biological Functions of Berberine: An Updated Critical Review / Bikarma Singh, Anil Kumar Katare
Summary Active botanical ingredients are a prime requirement for herbal formulations and discovering a drug is all about integration of science disciplines. In recent decades there has been a growing interest in treating wounds and diseases using traditional remedies based on local herbs, combined with chemical advances. Although this has led to the development of new bioactive ingredients from plants, there has been little success in terms of clinical trials and post-marketing studies to comply with FDA guidelines. Plants have been used as a source of medicine throughout history and continue to serve as the basis for many pharmaceuticals used today. However, despite the modern pharmaceutical industry being founded on botanical medicine, synthetic approaches to drug discovery have now become standard. Science-driven translational discovery and botanical development has created a new reality, leading to enormous changes in strategies, technologies and the disciplines involved, which have been embraced by the pharmaceutical and biotech industries. This book gathers scientific expertise and traditional knowledge to promote the discovery and development of new formulations and drugs based on active ingredients and to provide guidance on taking these to clinical trials. It discusses major topics, such as how the phytochemical composition of many plants has changed over time due to factors like cultivation, which can have both positive and negative effects on the levels of bioactive compounds. It also explores the importance of plants as a valuable source of therapeutic compounds as a result of their vast biosynthetic capacity, and classifies them according to their intended use, safety and regulatory status. Further, the book offers insights into the regulatory aspects of botanical products, which is an important issue when considering standardization and quality assessment, and also examines the commercial aspects of plant-derived medications and their proven role in the treatment of chronic diseases such as heart disease, high blood pressure, pain, asthma, and other associated conditions. Given its scope, this book is a valuable tool for botanists, natural product chemists, pharmacologists and microbiologists involved in the study of phytochemicals for drug discovery
Bibliography Includes bibliographical references
Subject Botanical drug industry.
Materia medica, Vegetable.
Pharmaceutical technology.
Drug resistance.
Drug Discovery
Plants, Medicinal
Phytochemicals -- therapeutic use
Phytotherapy -- methods
Phytotherapy
Technology, Pharmaceutical
Drug Resistance
Pharmacology.
Pharmaceutical technology.
Medical -- Pharmacology.
Medical -- Pharmacy.
Botanical drug industry
Materia medica, Vegetable
Drug resistance
Pharmaceutical technology
Form Electronic book
Author Singh, Bikarma, editor.
ISBN 9789811559174
9811559171