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Title Apoptosis : a practical approach / edited by George P. Studzinski
Published Oxford ; New York : Oxford University Press, [1999]
©1999
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Description 1 online resource (xxii, 244 pages) : illustrations (some color)
Series The practical approach series ; 216
Practical approach series ; 216
Contents Machine generated contents note: 1. Overview of apoptosis / George P. Studzinski -- 2. Morphological recognition of apoptotic cells / Christopher S. Potten / James W. Wilson -- 3. Assessment of DNA damage in apoptosis / Yves Pommier / Akira Yoshida / Rong-Guang Shao -- 4. Analysis of cell death by flow and laser-scanning cytometry / Elzbieta Bedner / Xun Li / Zbigniew Darzynkiewicz -- 5. Cell-mediated cytotoxicity and cell death receptors / Javier Naval / Alberto Anel -- 6. Sphingolipids as messengers of cell death / Gary M. Jenkins / Yusuf A. Hannun -- 7. Cytochemical detection of cytoskeletal and nucleoskeletal changes during apoptosis / Manon van Engeland / Bert Schutte / [et al.] / Anton H. N. Hopman -- 8. Metabolic alterations associated with apoptosis / Thomas G. Cotter / Ana P. Costa-Pereira -- 9. Methods of measuring Bcl-2 family proteins and their functions / [et al.] / Zhihua Xie / Shinichi Kitada / John C. Reed -- 10. Methods for detecting proteolysis during apoptosis in intact cells / April L. Blajeski / Scott H. Kaufmann
Summary This text is designed to provide conceptual outlines and detailed procedures for basic and advanced studies of cell death by apoptosis. Chapters on the recognition of apoptosis as distinguished from necrosis and nonspecific cell DNA damage, are followed by a systematic examination of the established and the principal novel methodologies utilized by some leading laboratories conducting research on apoptosis. The organization is on the lines of signalling for apoptosis, the apoptotic cascade, and the execution of apoptosis. A wide variety of procedures are provided which will enable the reader to participate in cutting-edge research
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Apoptosis -- Laboratory manuals.
Apoptosis.
Genre/Form Laboratory Manual.
Laboratory manuals.
Laboratory manuals.
Form Electronic book
Author Studzinski, George P.
ISBN 0585483582 (electronic bk.)
1280374721
9780585483580 (electronic bk.)
9781280374722