| Description |
1 online resource (630 pages) |
| Series |
Wiley Series in Operations Research and Management Science |
| Contents |
And ED Performance Comparison 323 9.6 Benefits and Impacts 330 9.7 Scientific Advances 335 Acknowledgments 336 References 337 10 A Multiobjective Simulation Optimization of the Macrolevel Patient Flow Distribution 341 ; Yunzhe Qiu and Jie Song 10.1 Introduction 341 10.2 Literature Review 343 10.3 Problem Description and Modeling 346 10.4 Methodology 350 10.5 Case Study: Adjusting Patient Flow for a Two-Level Healthcare System Centered on the Puth 354 10.6 Conclusions and the Future Work 367 Acknowledgments 368 References 369 11 Analysis of Resource Intensive Activity Volumes in us Hospitals 373 ; Shivon Boodhoo and Sanchoy Das 11.1 Introduction 373 11.2 Structural Classification of Hospitals 375 11.3 Productivity Analysis of Hospitals 377 11.4 Resource and Activity Database for us Hospitals 379 11.5 Activity-Based |
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And Warren D'Souza 7.1 Introduction 189 7.2 Tutorials of Predictive Modeling Techniques 191 7.3 Review of Recent Predictive Modeling Applications in Radiation Oncology 194 7.4 Modeling Pathologic Response of Esophageal Cancer to Chemoradiotherapy 199 7.5 Modeling Clinical Complications after Radiation Therapy 205 7.6 Modeling Tumor Motion with Respiratory Surrogates 211 7.7 Conclusion 215 References 215 8 Mathematical Modeling of Innate Immunity Responses of Sepsis: Modeling and Computational Studies 221 ; Chih-Hang J. Wu, Zhenshen Shi, David Ben-Arieh, and Steven Q |
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And Xi Zhang 4.1 Introduction 95 4.2 Basic Elements of ECG 96 4.3 Statistical Modeling of ECG for Disease Diagnosis 99 4.4 An Example: Detection of Obstructive Sleep Apnea from a Single ECG Lead 115 4.5 Materials and Methods 115 4.6 Results 118 4.7 Conclusions and Discussions 121 4.8 Conclusion 121 References 121 5 Modeling and Simulation of Measurement Uncertainty in Clinical Laboratories 127 ; Varun Ramamohan, James T. Abbott, and Yuehwern Yih 5.1 Introduction 127 5.2 Background and Literature Review 129 5.3 Model Development Guidelines 138 5.4 Implementation of Guidelines: Enzyme Assay Uncertainty Model 141 5.5 Discussion and Conclusions 152 References 154 6 Predictive Analytics: Classification in Medicine and Biology 159 ; Eva K |
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Brown 2.1 Introduction 31 2.2 Background 32 2.3 Methodology 37 2.4 Case Studies 46 2.5 Discussion 51 2.6 Conclusions 52 Acknowledgments 53 References 53 3 Characterization and Monitoring of Nonlinear Dynamics and Chaos in Complex Physiological Systems 59 ; Hui Yang, Yun Chen, and Fabio Leonelli 3.1 Introduction 59 3.2 Background 61 3.3 Sensor-Based Characterization and Modeling of Nonlinear Dynamics 65 3.4 Healthcare Applications 80 3.5 Summary 88 Acknowledgments 90 References 90 4 Statistical Modeling of Electrocardiography Signal for Subject Monitoring and Diagnosis 95 ; Lili Chen, Changyue Song, |
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LIST OF CONTRIBUTORS xvii PREFACE xxi PART I ADVANCES IN BIOMEDICAL AND HEALTH INFORMATICS 1 1 Recent Development in Methodology for Gene Network Problems and Inferences 3 ; Sung W. Han and Hua Zhong 1.1 Introduction 3 1.2 Background 5 1.3 Genetic Data Available 7 1.4 Methodology 7 1.5 Search Algorithm 13 1.6 PC Algorithm 15 1.7 Application/Case Studies 16 1.8 Discussion 23 1.9 Other Useful Softwares 23 Acknowledgments 24 References 24 2 Biomedical Analytics and Morphoproteomics: An Integrative Approach for Medical Decision Making for Recurrent or Refractory Cancers 31 ; Mary F. McGuire and Robert E |
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Lee 6.1 Introduction 159 6.2 Background 161 6.3 Machine Learning with Discrete Support Vector Machine Predictive Models 163 6.4 Applying DAMIP to Real-World Applications 170 6.5 Summary and Conclusion 182 Acknowledgments 183 References 183 7 Predictive Modeling in Radiation Oncology 189 ; Hao Zhang, Robert Meyer, Leyuan Shi, Wei Lu, |
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Matteson 13.1 Introduction 427 13.2 Temporal Ambulance Demand Estimation 429 13.3 Spatiotemporal Ambulance Demand Estimation 436 13.4 Conclusions 447 References 448 14 Mathematical Optimization and Simulation Analyses for Optimal Liver Allocation Boundaries 451 ; Naoru Koizumi, Monica Gentili, Rajesh Ganesan, Debasree DasGupta, Amit Patel, Chun-Hung Chen, Nigel Waters, and Keith Melancon 14.1 Introduction 452 14.2 Methods 454 14.3 Results 461 14.4 Conclusions 471 Acknowledgment 473 References 473 15 Predictive Analytics in 30-Day Hospital Readmissions for Heart Failure Patients 477 ; Si-Chi Chin, Rui Liu, and Senjuti B |
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Modeling of Hospital Operations 382 11.6 Resource use Profile of Hospitals from HUC Activity Data 389 11.7 Summary 395 References 396 12 Discrete-Event Simulation for Primary Care Redesign: Review and a Case Study 399 ; Xiang Zhong, Molly Williams, Jingshan Li, Sally A. Kraft, and Jeffrey S. Sleeth 12.1 Introduction 399 12.2 Review of Relevant Literature 400 12.3 A Simulation Case Study at a Pediatric Clinic 407 12.4 What-If Analyses 414 12.5 Conclusions 420 References 420 13 Temporal and Spatiotemporal Models for Ambulance Demand 427 ; Zhengyi Zhou and David S |
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Roy 15.1 Introduction 478 15.2 Analytics in Prediction Hospital Readmission Risk 479 15.3 Analytics in Recommending Intervention Strategies 485 15.4 Related Work 495 15.5 Conclusion 497 References 497 16 Heterogeneous Sensing and Predictive Modeling of Postoperative Outcomes 501 ; Yun Chen, Fabio Leonelli, and Hui Yang 16.1 Introduction 501 16.2 Research Background 504 16.3 Research Methodology 512 16.4 Materials and Experimental Design 529 16.5 Experimental Results 529 16.6 Discussion and Conclusions 536 Acknowledgments 537 References 537 17 Analyzing Patient-Physician Interaction in Consultation for Shared Decision Making 541 ; Thembi Mdluli, Joyatee Sarker, Carolina Vivas-Valencia, Nan Kong, and Cleveland G |
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Simpson 8.1 Background 221 8.2 System Dynamic Mathematical Model (SDMM) 223 8.3 Pathogen Strain Selection 224 8.4 Mathematical Models of Innate Immunity of Air 239 8.5 Discussion 247 8.6 Conclusion 254 References 254 PART II ANALYTICS FOR HEALTHCARE DELIVERY 299 9 Systems Analytics: Modeling and Optimizing ClinicWorkflow and Patient Care 301 ; Eva K. Lee, Hany Y. Atallah, Michael D. Wright, Calvin Thomas IV, Eleanor T. Post, Daniel T. Wu, and Leon L |
| Summary |
Features of statistical and operational research methods and tools being used to improve the healthcare industry With a focus on cutting-edge approaches to the quickly growing field of healthcare, Healthcare Analytics: From Data to Knowledge to Healthcare Improvement provides an integrated and comprehensive treatment on recent research advancements in data-driven healthcare analytics in an effort to provide more personalized and smarter healthcare services. Emphasizing data and healthcare analytics from an operational management and statistical perspective, the book details how analytical methods and tools can be utilized to enhance healthcare quality and operational efficiency. Organized into two main sections, Part I features biomedical and health informatics and specifically addresses the analytics of genomic and proteomic data; physiological signals from patient-monitoring systems; data uncertainty in clinical laboratory tests; predictive modeling; disease modeling for sepsis; and the design of cyber infrastructures for early prediction of epidemic events. Part II focuses on healthcare delivery systems, including system advances for transforming clinic workflow and patient care; macro analysis of patient flow distribution; intensive care units; primary care; demand and resource allocation; mathematical models for predicting patient readmission and postoperative outcome; physician patient interactions; insurance claims; and the role of social media in healthcare. Healthcare Analytics: From Data to Knowledge to Healthcare Improvement also features: Contributions from well-known international experts who shed light on new approaches in this growing area Discussions on contemporary methods and techniques to address the handling of rich and large-scale healthcare data as well as the overall optimization of healthcare system operations Numerous real-world examples and case studies that emphasize the vast potential of statistical and operational research tools and techniques to address the big data environment within the healthcare industry Plentiful applications that showcase analytical methods and tools tailored for successful healthcare systems modeling and improvement The book is an ideal reference for academics and practitioners in operations research, management science, applied mathematics, statistics, business, industrial and systems engineering, healthcare systems, and economics. Healthcare Analytics: From Data to Knowledge to Healthcare Improvement is also appropriate for graduate-level courses typically offered within operations research, industrial engineering, business, and public health departments. HUI YANG, PhD, is Associate Professor in the Harold and Inge Marcus Department of Industrial and Manufacturing Engineering at The Pennsylvania State University. His research interests include sensor-based modeling and analysis of complex systems for process monitoring/control; system diagnostics/ prognostics; quality improvement; and performance optimization with special focus on nonlinear stochastic dynamics and the resulting chaotic, recurrence, self-organizing behaviors. EVA K. LEE, PhD, is Professor in the H. Milton Stewart School of Industrial and Systems Engineering at the Georgia Institute of Technology, Director of the Center for Operations Research in Medicine and HealthCare, and Distinguished Scholar in Health System, Health Systems Institute at both Emory University School of Medicine and Georgia Institute of Technology. Her research interests include health-risk prediction; early disease prediction and diagnosis; optimal treatment strategies and drug delivery; healthcare outcome analysis and treatment prediction; public health and medical preparedness; large-scale healthcare/medical decision analysis and quality improvement; clinical translational science; and business intelligence and organization transformation |
| Notes |
And ED Performance Comparison 323 9.6 Benefits and Impacts 330 9.7 Scientific Advances 335 Acknowledgments 336 References 337 10 A Multiobjective Simulation Optimization of the Macrolevel Patient Flow Distribution 341 Yunzhe Qiu and Jie Song 10.1 Introduction 341 10.2 Literature Review 343 10.3 Problem Description and Modeling 346 10.4 Methodology 350 10.5 Case Study: Adjusting Patient Flow for a Two-Level Healthcare System Centered on the Puth 354 10.6 Conclusions and the Future Work 367 Acknowledgments 368 References 369 11 Analysis of Resource Intensive Activity Volumes in us Hospitals 373 Shivon Boodhoo and Sanchoy Das 11.1 Introduction 373 11.2 Structural Classification of Hospitals 375 11.3 Productivity Analysis of Hospitals 377 11.4 Resource and Activity Database for us Hospitals 379 11.5 Activity-Based |
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And Xi Zhang 4.1 Introduction 95 4.2 Basic Elements of ECG 96 4.3 Statistical Modeling of ECG for Disease Diagnosis 99 4.4 An Example: Detection of Obstructive Sleep Apnea from a Single ECG Lead 115 4.5 Materials and Methods 115 4.6 Results 118 4.7 Conclusions and Discussions 121 4.8 Conclusion 121 References 121 5 Modeling and Simulation of Measurement Uncertainty in Clinical Laboratories 127 Varun Ramamohan, James T. Abbott, and Yuehwern Yih 5.1 Introduction 127 5.2 Background and Literature Review 129 5.3 Model Development Guidelines 138 5.4 Implementation of Guidelines: Enzyme Assay Uncertainty Model 141 5.5 Discussion and Conclusions 152 References 154 6 Predictive Analytics: Classification in Medicine and Biology 159 Eva K |
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Brown 2.1 Introduction 31 2.2 Background 32 2.3 Methodology 37 2.4 Case Studies 46 2.5 Discussion 51 2.6 Conclusions 52 Acknowledgments 53 References 53 3 Characterization and Monitoring of Nonlinear Dynamics and Chaos in Complex Physiological Systems 59 Hui Yang, Yun Chen, and Fabio Leonelli 3.1 Introduction 59 3.2 Background 61 3.3 Sensor-Based Characterization and Modeling of Nonlinear Dynamics 65 3.4 Healthcare Applications 80 3.5 Summary 88 Acknowledgments 90 References 90 4 Statistical Modeling of Electrocardiography Signal for Subject Monitoring and Diagnosis 95 Lili Chen, Changyue Song, |
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Haley Jr 9.1 Introduction 302 9.2 Background 304 9.3 Challenges and Objectives 305 9.4 Methods and Design of Study 306 9.5 Computational Results, Implementation, |
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LIST OF CONTRIBUTORS xvii PREFACE xxi PART I ADVANCES IN BIOMEDICAL AND HEALTH INFORMATICS 1 1 Recent Development in Methodology for Gene Network Problems and Inferences 3 Sung W. Han and Hua Zhong 1.1 Introduction 3 1.2 Background 5 1.3 Genetic Data Available 7 1.4 Methodology 7 1.5 Search Algorithm 13 1.6 PC Algorithm 15 1.7 Application/Case Studies 16 1.8 Discussion 23 1.9 Other Useful Softwares 23 Acknowledgments 24 References 24 2 Biomedical Analytics and Morphoproteomics: An Integrative Approach for Medical Decision Making for Recurrent or Refractory Cancers 31 Mary F. McGuire and Robert E |
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Lee 6.1 Introduction 159 6.2 Background 161 6.3 Machine Learning with Discrete Support Vector Machine Predictive Models 163 6.4 Applying DAMIP to Real-World Applications 170 6.5 Summary and Conclusion 182 Acknowledgments 183 References 183 7 Predictive Modeling in Radiation Oncology 189 Hao Zhang, Robert Meyer, Leyuan Shi, Wei Lu, |
|
Matteson 13.1 Introduction 427 13.2 Temporal Ambulance Demand Estimation 429 13.3 Spatiotemporal Ambulance Demand Estimation 436 13.4 Conclusions 447 References 448 14 Mathematical Optimization and Simulation Analyses for Optimal Liver Allocation Boundaries 451 Naoru Koizumi, Monica Gentili, Rajesh Ganesan, Debasree DasGupta, Amit Patel, Chun-Hung Chen, Nigel Waters, and Keith Melancon 14.1 Introduction 452 14.2 Methods 454 14.3 Results 461 14.4 Conclusions 471 Acknowledgment 473 References 473 15 Predictive Analytics in 30-Day Hospital Readmissions for Heart Failure Patients 477 Si-Chi Chin, Rui Liu, and Senjuti B |
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Shields 17.1 Introduction 541 17.2 Literature Review 543 17.3 Our Recent Data Mining Studies 548 17.4 Future Directions 553 17.5 Concluding Remarks 557 References 55 |
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Simpson 8.1 Background 221 8.2 System Dynamic Mathematical Model (SDMM) 223 8.3 Pathogen Strain Selection 224 8.4 Mathematical Models of Innate Immunity of Air 239 8.5 Discussion 247 8.6 Conclusion 254 References 254 PART II ANALYTICS FOR HEALTHCARE DELIVERY 299 9 Systems Analytics: Modeling and Optimizing ClinicWorkflow and Patient Care 301 Eva K. Lee, Hany Y. Atallah, Michael D. Wright, Calvin Thomas IV, Eleanor T. Post, Daniel T. Wu, and Leon L |
| Subject |
Medical care -- Data processing.
|
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Medical care -- Information services
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Medical care -- Data processing.
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Medical care -- Information services.
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| Form |
Electronic book
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| Author |
Lee, Eva K., editor.
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Yang, Hui, editor.
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| ISBN |
1119374642 |
|
1119374669 |
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1118919408 |
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9781118919422 |
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9781119374640 |
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9781119374664 |
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