| Description |
1 online resource (1 PDF file (xv, 396 pages)) : illustrations |
| Series |
Neuromethods, 1940-6045 ; volume 160 |
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Springer protocols |
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Neuromethods ; 160. 0893-2336
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Springer protocols (Series) 1949-2448
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| Summary |
This volume looks at major clinical trials for motor and non-motor symptoms in Parkinson's Disease (PD) and covers important aspects, including trial design, sample selection, and outcome selection. Chapters in this book discuss topics such as toxin-based rodent or genetic models of PD; clinical trials for motor symptoms, L-DOPA related motor complications, and gait disorders; clinical trials for mood disorders, troubled sleep, autonomic dysfunction; and clinical trials for disease modifying therapies. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory or research center |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Series Preface...Dedication...Preface...Table of Contents...Contributing Authors... Part I Preclinical Models of Parkinson's Disease 1. Toxin-Based Rodent Models of Parkinson's Disease / M. Angela Cenci Nilsson and Véronique Sgambato 2. Assessment of Non-Motor Symptoms in Rodent Models of Parkinson's Disease / Francesca Rossi, Manolo Carta, and Elisabetta Tronci 3. Genetic Models of Parkinson's Disease / Philippe Kachidian and Paolo Gubellini Part II Clinical Trials for Motor Symptoms in Parkinson's Disease 4. A Review of Randomized Phase III Pharmacological Clinical Trials for Motor Symptoms in Parkinson's Disease Patients and Quality of Evidence Recommendations / Mónica M. Kurtis, Carmen Rodriguez-Blazquez, and Isabel Pareés 5. Clinical Trials for Motor Complications in Parkinson's Disease / Tiago A. Mestre, Joaquim J. Ferreira, and Olivier Rascol 6. Clinical Trials for Gait Disorders in Parkinson's Disease / Zuzana Kosutzka, Urban M. Fietzek, and Peter Valkovic 7 |
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Clinical Trials for Disease Modifying Agents in Parkinson's Disease / Orlando Artavia and Lana Chahine 8. Value and Methods of Pharmacovigilance in the Monitoring of Drug Safety in Parkinson's Disease Santiago / Perez-Lloret, James A.G. Crispo, Maria Veronica Rey, Donald Mattison, and Daniel Krewski Part III Clinical Trials for Non-Motor Symptoms in Parkinson's Disease 9. Clinical Trials for Cognitive Impairment and Dementia in Parkinson's Disease / Brandon Barton 10. Clinical Trials for Depression, Anxiety, Fatigue, and Apathy in Parkinson's Disease / Matej Skorvanek and Marek Balaz 11. Clinical Trials for Sleep Disorders and Daytime Somnolence in Parkinson's Disease / Marissa N. Dean and Amy W. Amara 12. Clinical Trials on Management of Pain in Parkinson's Disease / Azman Aris, Raquel Taddei, Alexandra Rizos, Anna Sauerbier, and K. Ray Chaudhuri 13. Clinical Trials for Orthostatic Hypotension in Parkinson's Disease and Other Synucleinopathies / Jose-Alberto Palma and Horacio Kaufmann 14. Clinical Trials for Erectile Dysfunction in Parkinson's Disease / Shen-Yang Lim, Ai Huey Tan, Mathis Grossmann 15. Clinical Trials for Constipation in Parkinson's Disease / Patricio Millar Vernetti |
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Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL |
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Description based on online resource; title from PDF title page (viewed October 28, 2021) |
| Subject |
Medicine.
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Neurosciences.
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Parkinson's disease.
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Symptomatic Parkinson's disease.
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Parkinson Disease
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Clinical Trials as Topic
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Medicine
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Neurosciences
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Parkinson Disease, Secondary
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medicines (material)
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medicine (discipline)
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Neurosciences.
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Medical -- Neuroscience.
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Symptomatic Parkinson's disease
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Parkinson's disease
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Medicine
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Neurosciences
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| Genre/Form |
Laboratory manuals.
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Manuels de laboratoire.
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| Form |
Electronic book
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| Author |
Perez-Lloret, Santiago, editor
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| ISBN |
9781071609125 |
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1071609122 |
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