| Description |
1 online resource |
| Contents |
Front Cover; Innovative Neuromodulation; Copyright Page; Contents; Biographies; List of Contributors; Preface; Acknowledgments; Introduction-Opportunities and Challenges; References; I. New Directions with Current Therapies; 1 Microarrays in the Brain: Can They Be Used for Brain-Machine Interface Control?; Building a Brain-Machine Interface; Neural Signal Resolution; Alternate Signal Types and Risk Factors; The Architecture of a Brain-Machine Interface; Signal Acquisition/Processing; Decoding; Command Recoding; End-Effector Actuation; What Does the Motor Cortex Do? |
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Movements Versus Muscles Debate in the Distant PastMovements Versus Muscles Debate in the Recent Past; The Representational Approach and Encoding Versus Decoding; Movements Versus Muscles Versus Other Stuff: The Debate Continues Endlessly; Confounded Variables Embedded Within Distributed Neural Circuits; Low Performance Level and Limited Ability to Generalize; Noise, Feedback, and Sparse Sampling; Can Anything Be Done to Improve Performance?; So the Answer to What the Motor Cortex Does Is ... ; Future Possibilities; Direct Control; Direct Control Versus Indirect Decoding; Concluding Remarks |
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AcknowledgmentsReferences; 2 Feedback-Sensitive and Closed-Loop Solutions; Introduction; Cranial Nerve Electrical Stimulation for Seizure Control; Brain Stimulation for Epilepsy: Historical Perspective; Brain Stimulation In Vitro and In Vivo; Thalamic Brain Stimulation; Location of Brain Stimulation; Electrical Parameters for Brain Stimulation; Possible Mechanisms of Action; Closed-Loop Brain Stimulation; Clinical Applications; Seizure Detection; The Responsive Neurostimulator System; The RNS System: Pivotal and Long-Term Results; Seizure Prediction; Adverse Effects and Technical Challenges |
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Closed-Loop Systems Leading to Waveform AdjustmentCoordinated Reset; Spinal Cord Stimulation; Other Considerations; References; II. New Modes of Therapy; 5 Ultrasound Neuromodulation; Introduction; Physics of Ultrasound; Historical Perspective of Ultrasonic Neuromodulation; Experimental Cortical Neuromodulation; Neuromodulation of Visual-Evoked Potentials; Experimental Neuromodulation of Deep Cerebral Structures; Hippocampal Neuromodulation With Ultrasound; Cortical Neuromodulation in Large Animals and Humans; Mechanisms of Ultrasonic Neuromodulation |
| Summary |
References; 3 Directional Deep Brain Stimulation; Deep Brain Stimulation Inhibits Neuronal Firing; DBS Hardware; Accurate DBS Lead Targeting and Placement is Critical for Success of the Therapy; Directional DBS Leads Confer Several Benefits; Directional DBS in Parkinson's Disease and Essential Tremor; Directional DBS Clinical Proof of Concept; Application of Directional DBS to Other Diseases; References; 4 Waveform Variation in Neuromodulation; Introduction; Modifications of Traditional Waveform Parameters and Shapes; Deep Brain Stimulation; Random or Irregular Signals in DBS |
| Notes |
Includes index |
| Bibliography |
References; 3 Directional Deep Brain Stimulation; Deep Brain Stimulation Inhibits Neuronal Firing; DBS Hardware; Accurate DBS Lead Targeting and Placement is Critical for Success of the Therapy; Directional DBS Leads Confer Several Benefits; Directional DBS in Parkinson's Disease and Essential Tremor; Directional DBS Clinical Proof of Concept; Application of Directional DBS to Other Diseases; References; 4 Waveform Variation in Neuromodulation; Introduction; Modifications of Traditional Waveform Parameters and Shapes; Deep Brain Stimulation; Random or Irregular Signals in DBS |
| Notes |
Online resource; title from PDF title page (ScienceDirect, viewed January 26, 2017) |
| Subject |
Neural stimulation.
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Neurotransmitter receptors.
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Deep Brain Stimulation
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Receptors, Neurotransmitter
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Neurotransmitter receptors.
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Neural stimulation.
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| Form |
Electronic book
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| Author |
Shils, Jay L., author.
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| ISBN |
9780128005965 |
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0128005963 |
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