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Title Heat shock proteins : potent mediators of inflammation and immunity / edited by Alexzander A.A. Asea and Antonio De Maio
Published Dordrecht ; [London] : Springer, [2007]
Online access available from:
Springer eBooks    View Resource Record  


Description 1 online resource (xii, 357 pages) : illustrations
Series Heat shock proteins ; v. 1
Heat shock proteins (Series) ; v. 1
Contents Front Matter; Release of Heat Shock Proteins: Passive Versus Active Release Mechanisms; Hsp70 Peptide Acting as a Danger Signal for Natural Killer (NK) Cells; Mechanisms of Stress-Induced Cellular Hsp72 Release; Roles of Extracellular Heat Shock Proteins: A New Sense of Danger; Macrophages and the Stress Response; Heat Shock Proteins and Scavenger Receptors; The Inside Story: Anti-Inflammatory roles of HSF1 and heat shock proteins; Interaction of Heat Shock Protein 60 with Innate Immune Cells; HSP-APC Interactions: Initiation of Immune Responses
Summary Heat Shock Proteins: Potent Mediators of Inflammation and Immunity currently provides the most up-to-date review on new mechanisms and provides exciting insights into how heat shock proteins modulates the hosts immune response. Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which heat shock proteins activate immune responses and provides answers as to its biological significance to the host. From the early stages of binding and receptors-mediated signalling, to new paradigms by which heat shock proteins are released into the circulation, to antigen processing and presentation, and finally to the immune response itself this book is a must read for graduate and postgraduates in the field of Biology (plant and mammal), Biochemistry (pro- and eukaryotic), Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Heat shock proteins.
Immune response -- Regulation.
Heat-Shock Proteins -- metabolism.
Inflammation Mediators -- immunology.
Inflammation -- immunology.
Form Electronic book
Author Asea, Alexzander A. A.
De Maio, Antonio.
ISBN 1402055846 (HB ; alk. paper)
9781402055843 (HB ; alk. paper)