| Description |
1 online resource |
| Contents |
Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Part 1 Healthy Skin Microbiome -- Chapter 1 The Microbiome of Healthy Skin -- 1.1 Introduction -- 1.1.1 Retrospective -- 1.1.2 Next Generation Sequencing -- 1.2 The Skin Microbiome in Health -- 1.2.1 Composition -- 1.2.2 Diversity -- 1.2.3 Uniqueness -- 1.3 Healthy Skin is the Foundation of a Balanced Skin Microbiome -- 1.3.1 Physical Aspects of Skin Impacting the Microbiome -- 1.3.2 Biochemical and Defensive Aspects of Skin Impacting the Microbiome -- 1.3.2.1 The Acid Mantle -- 1.3.2.2 Antimicrobial Lipids (AMLs) |
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1.3.2.3 Antimicrobial Peptides (AMPs) -- 1.3.3 Nutritional and Microenvironmental Aspects of Skin Impacting the Microbiome -- 1.3.3.1 Amino Acids -- 1.3.3.2 Sebaceous Lipids -- 1.3.3.3 Organic Acids and Other Materials -- 1.4 A Balanced Skin Microbiome Supports the Normal Functioning of Healthy Skin -- 1.4.1 Pathogen Exclusion -- 1.4.2 Contribution to Skin pH -- 1.4.3 Microbial Contribution to Skin Barrier Integrity -- 1.5 Conclusion -- Acknowledgments -- References -- Chapter 2 The Gut Microbiome-Skin Axis: Impact on Skin and Systemic Health -- 2.1 Introduction |
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2.2 The Gut-Skin Microbiome Axis -- 2.3 The Gut-Skin Microbiome Axis: Principle Pathways -- 2.4 Dysbiosis of the Gut Microbiome and Skin Dyshomeostasis -- 2.4.1 Acne Vulgaris -- 2.4.2 Atopic Dermatitis -- 2.5 Summary and Future Directions -- References -- Chapter 3 The Skin and Oral Microbiome: An Examination of Overlap and Potential Interactions between Microbiome Communities -- 3.1 Introduction -- 3.1.1 Focus of the Chapter -- 3.1.2 Definition of Skin Microbiome -- 3.1.3 Definition of Oral Microbiome -- 3.2 Characterization of the Microbiome |
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3.2.1 Variability and Stability of Skin and Oral Microbiome -- 3.2.2 Microbial Community -- 3.2.2.1 Permeant Mutualistic or Commensal Microbes -- 3.2.2.2 Non-Pathogenic Transient Microbes -- 3.2.2.3 Pathogenic Microbes -- 3.3 The Core Skin and Oral Microbiomes -- 3.3.1 Taxonomic Methodology -- 3.3.2 Subgroups of the Microbiome -- 3.3.2.1 Bacteriome -- 3.3.2.2 Mycobiome (and Other Eukaryotic Microbial Members) -- 3.3.2.3 Virome -- 3.4 Interactions Between Skin and Oral Microbiomes -- 3.4.1 Potential for Interactions -- 3.4.2 Quorum Sensing -- 3.4.3 Immune System Development |
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3.4.4 Future Directions -- 3.5 Conclusion -- Acknowledgments -- References -- Part 2 Skin Microbiome Observational Research -- Chapter 4 Skin Microbiome Alterations in Skin Diseases -- 4.1 Introduction and Background -- 4.2 Interactions Between Microbes and Host -- 4.3 Summary of Known Associations Between Skin Dysbioses and Skin Diseases -- 4.3.1 The Role of -- in Skin Disease -- 4.3.2 Atopic Dermatitis -- 4.3.3 Acne Vulgaris -- 4.3.4 Psoriasis -- 4.4 Skin Dysbioses in Skin Health -- 4.5 Other Skin Conditions -- 4.6 Therapeutic Approaches to Dysbiosis-Associated Skin Diseases |
| Summary |
"In the past decade, interest and technology have greatly advanced to unravel the nature and effect of skin microbiome on our health. Diseases such as atopic dermatitis and acne are at the forefront of this research, but also other conditions such as skin cancer are under investigation. In addition, mapping of the skin microbiome has gone from basic to more detailed with attempts to correlate it to various ages, ethnicities and genders. In parallel to mapping it, great deal of research is dedicated to understanding its functionality and communication (and hence effect) on human cells. The interest and growing knowledge also gave rise to the development of various models in vitro and ex vivo as well as collection and sequencing techniques in clinical studies. While science evolves, the regulatory and legal framework is slowly shaping but various issues are yet to be determined and are described in the book"-- Provided by publisher |
| Subject |
Dermatology.
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Skin -- Diseases.
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Dermatology
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Skin Diseases
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Dermatology
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Skin -- Diseases
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| Form |
Electronic book
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| Author |
Dayan, Nava, editor
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| ISBN |
9781119593041 |
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1119593042 |
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