| Description |
1 online resource (xii, 452 pages) : illustrations (some color) |
| Series |
Biological and medical physics, biomedical engineering |
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Biological and medical physics, biomedical engineering.
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| Contents |
Intro -- Preface -- Tribute to Assoc. Prof. Ekaterina Borisova -- Contents -- Part I Stokes Mueller Based Polarimetry -- 1 Polarization Imaging of Optical Anisotropy in Soft Tissues -- 1 Introduction -- 2 Polarization Fundamentals -- 2.1 Optical Anisotropy -- 2.2 Polarization -- 2.3 Polarization Properties -- 2.3.1 Linear Retardance -- 2.3.2 Circular Retardance -- 2.3.3 Linear Diattenuation -- 2.3.4 Circular Diattenuation -- 2.4 Mueller-Stokes Formalism -- 2.5 Decomposition -- 3 Instrumentation -- 3.1 Polarimeter Architectures -- 4 Applications -- 4.1 Quantitative Polarized Light Microscopy |
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4.2 Mueller Matrix Imaging -- 4.3 Polarized Spatial Frequency Domain Imaging -- 4.4 Optomechanical Testing -- 5 Conclusion -- References -- 2 Polarization Techniques in Biological Microscopy -- 1 Optical Properties of Biological Samples -- 2 Polarized Microscopy -- 3 Polarized Light Microscopy Approaches -- 3.1 Wide-Field Polarized Microscopy -- 3.2 Polarized Fluorescence Microscopy -- 3.3 Polarized Total Internal Reflection Fluorescence Microscopy -- 3.4 Confocal Scanning Laser Polarimetric Microscopy -- 3.5 Polarization-Sensitive Second Harmonic Microscopy -- References |
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3 Stokes -Mueller Matrix Polarimetry: Effective Parameters of Anisotropic Turbid Media: Theory and Application -- 1 Introduction -- 2 Stokes Vector and Mueller Matrix Formalism -- 3 Decomposition Mueller Matrix for Extracting Effective Optical Parameters -- 4 Experimental Results and Discussion -- 4.1 Optical Fibers and Free-Space Media -- 4.2 Baked Polarizer (LB and LD Properties) -- 4.3 Depolarizer (LDep and CDep Properties) -- 4.4 Quarter-Wave Plate and Depolarizer (LB, LDep, and CDep Properties) -- 4.5 Dissolved Glucose Aqueous Solution (CB, LDep, and CDep Properties) |
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4.6 Healthy and Nonmelanoma-Induced Mouse Skin Tissue Sample -- 4.7 Human Blood Plasma -- 4.8 Collagen Solution -- 4.9 Healthy and Cancerous Human Skin Tissue -- 4.10 Combination of Effective Parameters and Artificial Intelligent Classification Models for Human Skin Detection -- 5 Conclusion -- References -- 4 Mueller Matrix Imaging -- 1 Introduction -- 2 Polarimetric Optical Properties -- 2.1 Physical Origin of Polarimetric Effects -- 2.2 Quantitative Interpretation of Mueller Matrix Polarimetry Data -- 3 Imaging MM Instrumentation -- 3.1 System Based on Two Rotating Compensators |
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3.2 Systems Based on Tunable Liquid Crystals Compensators -- 3.3 Use of Polarization Cameras for MM Imaging -- 4 Practical Considerations and Examples -- 5 Summary and Outlook -- References -- 5 Biological Imaging Through Optical Mueller Matrix Scanning Microscopy -- 1 Introduction -- 2 Complete Mueller Matrix Measurements -- 2.1 Back to the Mueller Matrix Formalism -- 2.2 Interpreting the Mueller Matrix -- 2.3 Optical Scanning Microscopy Architecture -- 2.4 Calibration of the SLM Mueller Matrix -- 3 Optical Scanning Imaging Architecture -- 3.1 Temporal Domain -- 3.2 Spectral Domain |
| Summary |
This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Description based on online resource; title from digital title page (viewed on October 16, 2023) |
| Subject |
Polarization microscopy.
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Biology -- Research.
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Medicine -- Research.
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Biology -- Research
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Medicine -- Research
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Polarization microscopy
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| Form |
Electronic book
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| Author |
Mazumder, Nirmal, editor.
|
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Kistenev, Yury V., editor.
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Borisova, Ekaterina, editor.
|
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K., Shama Prasada, editor
|
| ISBN |
9783031318528 |
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3031318528 |
|
