Title Statistical human genetics : methods and protocols / edited by Robert C. Elston

Edition Second edition Published New York : Humana Press : Springer, ©2017

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Description 1 online resource (xii, 689 pages) : illustrations Series Methods in molecular biology, 1064-3745 ; 1666 Methods in molecular biology (Clifton, N.J.) ; v. 1666. 1064-3745 Contents Statistical genetic terminology / Robert C. Elston, Jaya Satagopan, and Shuying Sun -- Identification of genotype errors / Jeffery O'Connell and Yin Yao -- Detecting pedigree relationship errors / Lei Sun -- Identifying cryptic relationships / Lei Sun, Apostolos Dimitromanolakis, and Wei-Min Chen -- Estimating allele frequencies / Indra Adrianto and Courtney Montgomery -- Testing departure from hardy-weinberg proportions / Jian Wang and Sanjay Shete -- Estimating disequilibrium coefficients / Maren Vens and Andreas Ziegler -- Detecting familial aggregation / Adam C. Naj and Terri H. Beaty -- Estimating heritability from twin studies / Katrina L. Grasby, Karin J.H. Verweij, Miriam A. Mosing, Brendan P. Zietsch, and Sarah E. Medland -- Estimating heritability from nuclear family and pedigree data / Murielle Bochud -- Correcting for ascertainment / Warren Ewens and Robert C. Elston -- Segregation analysis using the unified model / Xiangqing Sun -- Design considerations for genetic linkage and association studies / Jeremie Nsengimana and D. Timothy Bishop -- Model-based linkage analysis of a quantitative trait / Yeunjoo E. Song, Sunah Song, and Audrey H. Schnell -- Model-based linkage analysis of a binary trait / Rita M. Cantor -- Model-free linkage analysis of a quantitative trait / Nathan J. Morris and Catherine M. Stein -- Model-free linkage analysis of a binary trait / Wei Xu, Jin Ma, Celia M.T. Greenwood, Andrew D. Paterson, and Shelley B. Bull -- Single marker association analysis for unrelated samples / Gang Zheng, Ao Yuan, Qizhai Li, and Joseph L. Gastwirth -- Single marker family-based association analysis conditional on parental information / Ren-Hua Chung, Daniel D. Kinnamon, and Eden R. Martin -- Single marker family-based association analysis not conditional on parental information / Junghyun Namkung and Sungho Won -- Calibrating population stratification in association analysis / Huaizhen Qin and Xiaofeng Zhu -- Cross-phenotype association analysis using summary statistics from GWAS / Xiaoyin Li and Xiaofeng Zhu -- Haplotype inference / Sunah Song, Xin Li, and Jing Li -- Multi-SNP haplotype analysis methods for association analysis / Daniel O. Stram -- Analysis of ethnic mixtures / Xiaofeng Zhu and Heming Wang -- Detecting multiethnic rare variants / Weiwei Ouyang, Xiaofeng Zhu, and Huaizhen Qin -- Identifying gene interaction networks / Danica Wiredja and Gurkan Bebek -- Structural equation modeling / Catherine M. Stein, Nathan J. Morris, Noemi B. Hall, and Nora L. Nock -- Mendelian randomization / Sandeep Grover, Fabiola Del Greco M., Catherine M. Stein, and Andreas Ziegler -- Preprocessing and quality control for whole-genome sequences from the illumina HiSeq X platform / Marvin N. Wright, Damian Gola, and Andreas Ziegler -- Processing and analyzing human microbiome data / Xuan Zhu, Jian Wang, Cielito Reyes-Gibby, and Sanjay Shete Bibliography Includes bibliographical references and index Subject Human genetics -- Statistical methods Biochemical markers. Statistics. Decision making -- Mathematical models. Nucleic acid hybridization. Phenotype. Genetics -- Technique. Medical genetics. Genetic markers. Genetics Sequence Analysis Microarray Analysis Biomarkers Statistics as Topic Decision Support Techniques Molecular Probe Techniques Nucleic Acid Hybridization Phenotype Genetic Techniques Microchip Analytical Procedures Epidemiologic Methods Investigative Techniques Medical Informatics Applications Genetic Phenomena Medical Informatics Chemistry Techniques, Analytical Information Science Genetics, Medical Oligonucleotide Array Sequence Analysis Data Interpretation, Statistical Genetic Markers statistics. Medical genetics. Medical -- Genetics. Statistics Phenotype Nucleic acid hybridization Medical genetics Genetics -- Technique Genetic markers Decision making -- Mathematical models Biochemical markers Human genetics -- Statistical methods Genre/Form Laboratory manuals. Manuels de laboratoire. Form Electronic book Author Elston, Robert C., 1932- ISBN 9781493972746 149397274X 1493972731 9781493972739

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