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Book Cover
E-book

Title Clinical guide to heart transplantation / Jon Kobashigawa, editor
Published Cham, Switzerland : Springer, [2017]
©2017

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Description 1 online resource : color illustrations
Contents Introduction; Author Biography; Contents; Contributors; 1: Medical and€Device Options for€Patients with€End-Stage Heart Failure; Introduction; Medical and€Pharmacological Management of€End-Stage Heart Failure; Angiotensin Receptor-Neprilysin Inhibitors (ARNIs); Angiotensin-Converting Enzyme (ACE) Inhibitors and€Angiotensin Receptor Blockers (ARBs); Diuretics; Beta-Blockers; Ivabradine; Aldosterone-Receptor Antagonists; Hydralazine and€Isosorbide Dinitrate; Digoxin; Anticoagulation; Fluid Restriction; Inotropic Agents; Device Management of€End-Stage Heart Failure
Cardiac Resynchronization Therapy Implantable Cardioverter- Defibrillator (ICD); Further Options; Palliative Approaches to€Heart Failure; References; 2: Mechanical and€Surgical Options for€Patients with€End-Stage Heart Failure; Introduction; Ventricular Assist Device Categories: A€Generational History; Total Artificial Heart; Trends in€Ventricular Assist Device Use: Strategies and€Outcomes; Contraindications to€LVAD Insertion; INTERMACS Scale and€Risk Factors for€Mortality Post-implant; Potential Complications of€Left Ventricular Assist Devices
Left Ventricular Assist Device Selection Short Term Options for€Mechanical Circulatory Support; Intra-aortic Balloon Pump; Extracorporeal Membrane Oxygenation; Percutaneous Mechanical Circulatory Support; Cardiac Transplantation; References; 3: Evaluation for€Heart Transplant Candidacy; Introduction; Indications for€Cardiac Transplantation; Evaluation Testing; Cardiopulmonary Exercise Testing; Maximal Oxygen Consumption; Hemodynamic Performance Assessment; Heart Failure Survival Score (HFSS); The Seattle Heart Failure Model (SHFM); Other Factors
Potential Contraindications to€Cardiac Transplantation Age; Obesity; Malignancy; Pulmonary Hypertension; Primary Pulmonary Disease; Diabetes Mellitus; Renal Dysfunction; Peripheral Vascular Disease; Frailty; Infections; HIV; Hepatitis B; Hepatitis C; Tuberculosis; Chagas Disease; Substance Use; Other Systemic Diseases; Psychosocial Evaluation; Financial Considerations; References; 4: Listing, Donor Allocation and€Optimization of€the Pre-Ưtransplant Patient; Introduction; Listing Process; Allocation Criteria; A Brief History; Current System
Organ Procurement Organizations Urgency-Based Tiers; Current Controversies in€Heart Allocation; The Future of€Heart Allocation: A€Further-Tiered System?; Optimization of€the€Pre-transplant Patient; Medical Surveillance on€the€Waitlist; Immunological Optimization; Other Considerations for€the€Wait-ƯListed Patient; Pre-operative Preparation of€the€Patient for€Transplantation; References; 5: Overview of€Transplantation Immunobiology; Innate Versus Adaptive Immunity; Overview and€Polymorphism of€HLA; Alloantigen Presentation/Cell Mediated Rejection
Summary This handbook is an easy reference for those involved in the management of heart transplant. While this compilation of best practices cannot address the complexity of the individual patients we care for on a daily basis, it will serve to help us ask the right questions, access the best evidence and ultimately make the best decisions for the patients involved. Clinical Guide to Heart Transplantation provides a current review of the field of heart transplantation and how it has evolved into an established therapy for the treatment of end-stage heart failure. With the advent of improved surgical techniques, the development of immunosuppressive drugs and the utilization of more sophisticated monitoring strategies and treatments for graft rejection, heart transplantation now offer patients an avenue to both improved survival and quality of life. With over 4000 heart transplants performed per year globally and with 1-year survival approaching 90%, this practical title assists those involved in the this most complex of procedures to establish best practice. It is therefore essential reading for all practitioners in this field, charged with making critical decisions in the management of patients, donor organs, and the transplant process itself in order to achieve the greatest benefit in the utilization of this often scarce resource
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (EBSCO, viewed April 5, 2017)
Subject Heart -- Transplantation.
Heart Transplantation
Postoperative Complications -- immunology
Postoperative Complications -- prevention & control
MEDICAL -- Surgery -- General.
Heart -- Transplantation
Form Electronic book
Author Kobashigawa, Jon A., editor.
ISBN 9783319437736
3319437739