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Book Cover
E-book
Author Carlson, Bruce M

Title Muscle Biology The Life History of a Muscle
Published San Diego : Elsevier Science & Technology, 2021

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Description 1 online resource (214 p.)
Contents Front Cover -- MUSCLE BIOLOGY -- Muscle Biology -- Copyright -- Contents -- Sources of borrowed figures -- Preface -- Introduction -- 1 -- Mature skeletal muscle-An overview -- The many structural dimensions of muscle -- The neuromuscular junction -- Muscle fiber contraction -- Contractile properties of single muscle fibers and muscle fiber types -- Motor units -- The sensory apparatus of a muscle -- Contraction of an entire muscle -- The role of internal architecture in muscle function -- The role of connective tissue in whole muscle contraction
Tendons and their connection to muscle and bone -- The myotendinous junction -- The enthesis-the connection between tendon and bone -- Muscle contractions and whole-body movements -- References -- 2 -- Embryonic origins of skeletal muscle -- Origins and cellular migrations -- Morphogenesis of a muscle -- Myogenesis -- References -- 3 -- Normal muscle growth -- Prenatal muscle fiber formation -- Development of muscle fiber types -- Satellite cells and postnatal muscle growth -- Myostatin and the control of muscle growth -- The intrauterine and early postnatal growth environment for muscle
Metabolic pathways that foster growth -- Systemic factors influencing intrauterine and early postnatal growth -- Factors influencing intrauterine muscle growth -- Factors influencing postnatal muscle growth -- References -- 4 -- Muscle adaptation to increased use -- Muscle adaptations to increased load (strength training) or increased duration of use (endurance training) -- Adaptations to increased load (hypertrophy) -- Adaptations to increased duration of use (endurance exercise) -- Reversal of training gains -- Adaptation to changes in length -- References
5 -- Muscle adaptation to decreased use -- Conditions leading to muscle atrophy -- Denervation -- Conditions leading to atrophy of innervated muscles -- The metabolic and molecular basis of muscular atrophy -- UPP pathway -- Calpains and caspases -- Autophagy -- Noncoding RNAs -- References -- 6 -- Muscle injury and regeneration -- The epimorphic regeneration of skeletal muscle -- The tissue regeneration of skeletal muscle -- Types of muscle damage leading to regeneration -- The role of muscle fiber damage and inflammation in muscle regeneration -- Activation of satellite cells
Regenerative myogenesis -- Gross morphogenesis and internal architecture -- Functional maturation -- Regeneration of muscle spindles -- References -- 7 -- Muscle disorders -- Disorders of muscle fibers -- Disorders of the neuromuscular junction -- Disorders of the sarcolemma and endomysium -- Other disorders of the muscle fiber -- Other disorders affecting muscles -- Metabolic myopathies -- Inflammatory myopathies -- Toxic myopathies -- Fibrosis -- References -- 8 -- The aging of muscle -- Broad measures of aging effects on skeletal muscle -- The structural basis for muscle loss during aging
Notes Description based upon print version of record
Performance measures of aging muscle
Subject Muscles.
Muscles
Muscles
Form Electronic book
ISBN 9780128202791
0128202793