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Book Cover
E-book
Author Pullaiah, T.

Title Forskolin : natural sources, pharmacology and biotechnology / T. Pullaiah
Published Singapore : Springer, 2022

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Description 1 online resource
Contents Intro -- Preface -- Contents -- About the Author -- 1: Coleus forskohlii-A Multipurpose Medicinal Plant -- 1.1 Introduction -- References -- 2: Botany of Coleus forskohlii -- 2.1 Introduction -- 2.2 Botany of Coleus forskohlii -- 2.3 Chromosome Number -- 2.4 Genetic Improvement -- 2.5 Mutation Breeding -- References -- 3: Traditional Medicinal Uses and Pharmacognosy of Coleus forskohlii -- 3.1 Introduction -- 3.2 Uses in Traditional Systems of Medicine -- 3.3 Ethnobotanical Uses -- 3.3.1 Digestive System -- 3.3.2 Nervous System -- 3.3.3 Skin -- 3.3.4 Respiratory System
3.3.5 Pain, Inflammation, and Musculoskeletal Problems -- 3.3.6 Metabolic and Endocrine System -- 3.3.7 Cardiovascular System -- 3.3.8 Sensory -- 3.3.9 Infection -- 3.4 Pharmacognosy -- 3.4.1 Macroscopic Characters of Root -- 3.4.2 Microscopic Characters -- 3.4.3 Study of Powder -- 3.4.4 Phytochemical Studies -- 3.4.4.1 Powder Analysis of Whole Plant -- 3.4.4.2 Physicochemical Analysis of Whole Plant of C. forskohlii (Disticraj and Jayaraman 2015) -- 3.5 Conclusion -- References -- 4: Chemistry of Coleus forskohlii Briq. -- 4.1 Introduction -- 4.2 Biogenesis -- 4.2.1 Forskolin
4.2.2 Molecular Approach -- 4.2.2.1 Bioengineering Process for Biosynthesis of Forskolin -- 4.2.2.2 Genkwanin -- 4.2.3 Extraction and Separation of Forskolin -- 4.2.4 Protocol for Separation and Preparation of Pure Forskolin -- 4.3 Phytocompounds Isolated from C. forskohlii -- 4.4 Prospective of Bioengineering of Forskolin -- 4.5 Conclusion -- References -- 5: Pharmacology of Coleus forskohlii and Forskolin -- 5.1 Introduction -- 5.2 Pharmacological Properties -- 5.2.1 Antiobesity -- 5.2.2 Antidiabetic Effect -- 5.2.3 Antithrombotic Effect -- 5.2.4 Cardiovascular Effects -- 5.2.5 Cystic Fibrosis
5.2.6 Glaucoma -- 5.2.7 Asthma -- 5.2.8 Anticancer Activity -- 5.2.9 Antioxidant Activity -- 5.2.10 Anti-Inflammatory Activity -- 5.2.11 Antidepressant Effect -- 5.2.12 Antistress Effect -- 5.2.13 Antidyspeptic Activity -- 5.2.14 Anti-Ulcer Activity -- 5.2.15 Hepatoprotective Activity -- 5.2.16 Antimicrobial Activity -- 5.2.17 Hypothyroidism -- 5.2.18 Skin Problems -- 5.2.19 Antispasmodic Effect -- 5.2.20 Protection against Gastric Ulcers -- 5.2.21 Bone Formation -- 5.2.22 Nerve Regeneration -- 5.2.23 Functional Neural Differentiation of Human Adipose Tissue-Derived Stem Cells
5.2.24 Neuronal Acetylcholinesterase Inhibitor -- 5.2.25 Antipsoriasis Effect -- 5.2.26 Anticonvulsant Activity -- 5.2.27 Neurological Disorders -- 5.2.28 Immunomodulator Activity -- 5.2.29 Analgesic Activity -- 5.2.30 Antiprotozoal Activity -- 5.2.31 Antimalarial Activity -- 5.2.32 Anthelmintic Activity -- 5.2.33 Gastroprotective and Anti-Helicobacter pylori Effects -- 5.2.34 Other Uses -- 5.3 Nano-Emulsions and Nanoparticles as Vehicles for Topical Delivery of Forskolin -- 5.4 Intestinal Permeability of Forskolin -- 5.5 Effects on Pregnancy -- 5.6 Toxicological Studies
Summary This monograph compiles updated information about forskolin, a labdane diterpene that is produced by the Coleus plant. Forskolin has a large number of practical uses and the book delves into the various aspects of this chemical. It includes topics such as the botanical source of forskolin and the cultivation of Coleus forskohlii, source. It also covers the biosynthetic pathways in natural sources and also through different biotechnological applications. Chapters include the potential and products in the Forskolin market. The book also covers the methods for enhanced production of forskolin from natural sources and through tissue culture methods for improvement of the plant for higher content of forskolin. It discusses the role of endophytes in the production of forskolin. The book is useful for students and researchers in the field of botany, pharmacology and biochemistry. It also serves scientists in various pharmaceutical industries
Bibliography Includes bibliographical references
Notes Online resource; title from PDF title page (SpringerLink, viewed November 4, 2022)
Subject Forskolin.
Colforsin
Forskolin
Terpens.
Genre/Form Llibres electrònics.
Form Electronic book
ISBN 9789811965210
9811965218