| Description |
1 online resource (xiv, 806 pages) : illustrations (chiefly color) |
| Contents |
Part I: General principles and regulations. Laboratory animals in India: past, present, and future -- Laws, regulations, policies and guidelines governing the care and use of laboratory animals -- Ethics, animal welfare and regulation: the Indian perspective -- Planning and designing of laboratory animal facilities -- Quality control of laboratory animals -- Basic biostatistics for laboratory animal science -- Alternatives to animal experiments in research and regulatory testing -- Part II: Biology and husbandry of laboratory animals. The anatomy and physiology of laboratory mouse -- The anatomy and physiology of laboratory rat -- The anatomy, physiology, and husbandry of laboratory rabbit -- The laboratory guinea pig -- The laboratory hamster -- The housing and husbandry of zebrafish (danio rerio) in a laboratory environment -- Nonhuman primates in biomedical research -- Mouse genetics and breeding -- Laboratory animal nutrition -- Bacterial and parasitological diseases in laboratory animals -- Microbiology and pathology of viral diseases in laboratory animals -- Laboratory animal behaviour and its applications in biomedical research -- Part III: Laboratory animal techniques and practices. Nonsurgical techniques in laboratory animals -- Clinical examination of laboratory rodents and rabbits -- Anaesthesia, analgesia and euthanasia of laboratory rodents and rabbits: a practical approach -- Biosafety consideration in laboratory animal facilities and working on infectious agents -- Occupational health hazards and disaster management in laboratory animal facilities -- Preclinical imaging for laboratory rodents -- Part IV: Specialty areas of laboratory animal science. Management of specific pathogen-free (SPF) mice and rats -- Good laboratory practice (GLP) requirements for preclinical animal studies -- Assisted reproductive technologies (ARTs) in the laboratory mouse -- Generating transgenic animal models: recent technological advancements -- Mouse models of the humanized immune system -- Necropsy procedures for laboratory animals -- Surgical models of laboratory animals |
| Summary |
"This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research. It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals. Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques. The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine"--Publisher's description |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from electronic title page (ProQuest Ebook Central, viewed October 19, 2021) |
| Subject |
Laboratory animals.
|
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Animal models in research.
|
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Animal experimentation.
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Laboratory Animal Science -- methods
|
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Animals, Laboratory
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Animal Experimentation
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Models, Animal
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Animal models in research
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Animal experimentation
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Laboratory animals
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| Form |
Electronic book
|
| Author |
Nagarajan, Perumal., editor
|
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Gudde, Ramachandra, editor
|
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Srinivasan, Ramesh (Veterinary phamacologist), editor
|
| ISBN |
981160987X |
|
9789811609879 |
|
