| Description |
1 online resource (xxxvii, 573 pages) : illustrations (some color) |
| Series |
Metal Ions in Life Sciences, 1559-0836 ; volume 13 |
|
Metal ions in life sciences ; v. 13. 1559-0836
|
| Contents |
Metal Ions and Infectious Diseases. An Overview from the Clinic -- Sodium and Potassium in Health and Disease -- Magnesium in Health and Disease -- Calcium in Health and Disease -- Vanadium. Its Role for Humans -- Chromium: Is It Essential, Pharmacologically Relevant or Toxic? -- Manganese in Health and Disease -- Iron: Effect of Deficiency and Overload -- Cobalt: Its Role in Health and Disease -- Nickel and Human Health -- Copper: Effects of Deficiency and Overload -- Zinc and Human Disease -- Molybdenum in Human Health and Disease -- Silicon: The Health Benefits of a Metalloid -- Arsenic. Can this Toxic Metalloid Sustain Life? -- Selenium. Role of the Essential Metalloid in Health |
| Summary |
MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases |
| Analysis |
biomedische wetenschappen |
|
biomedicine |
|
voedselchemie |
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food chemistry |
|
voedselwetenschappen |
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food sciences |
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humane ziekten |
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human diseases |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references at the end of each chapters and index |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed February 3, 2014) |
| Subject |
Metal ions -- Physiological effect
|
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Metals in the body.
|
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SCIENCE -- Life Sciences -- Biochemistry.
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Metal ions -- Physiological effect
|
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Metals in the body
|
| Form |
Electronic book
|
| Author |
Sigel, Astrid, editor
|
|
Sigel, Helmut, editor
|
|
Sigel, Roland K. O., editor
|
| ISBN |
9789400775008 |
|
9400775008 |
|
9400774990 |
|
9789400774995 |
|
