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Title Potential impact of individual genetic susceptibility and previous radiation exposure on radiation risk for astronauts / recommendations of the National Council on Radiation Protection and Measurements
Published Bethesda, Md. : National Council on Radiation Protection and Measurements, [2011]
©2011
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Description 1 online resource (xi, 180 pages)
Series NCRP report ; no. 167
NCRP report ; no. 167
Contents ""Cover""; ""Preface""; ""Contents""; ""Executive Summary""; ""1. Introduction""; ""1.1 Purpose of the Report""; ""1.2 Contents of the Report""; ""1.2.1 Introduction""; ""1.2.2 Radiation Exposures Received Over Lifetimes of Astronauts""; ""1.2.3 Biology Pertinent to Variations in Individual Susceptibility with Respect to Radiation Risks for Astronauts""; ""1.2.4 Predicting Cancer Risks from Previous Radiation or Chemotherapy Treatments""; ""1.2.5 Basis for Considering Medical Treatment, Disease, and Genetic Background in the NASA Occupational Radiation Protection Program""
""1.2.6 Regulatory and Statutory Issues""""1.2.7 Ethical Issues of Radiation Exposure, Genetic Background, and Astronaut Selection for Space Missions""; ""1.2.8 Background Issues, Conclusions, and Recommendations""; ""2. Radiation Exposures Received Over Lifetimes of Astronauts""; ""2.1 Radiation Protection Quantities""; ""2.1.1 Absorbed Dose""; ""2.1.2 Categories of Radiation-Induced Biological Effects""; ""2.1.3 Radiation Protection Quantities for Deterministic Effects""; ""2.1.4 Radiation Protection Quantities for Stochastic Effects""; ""2.2 Sources of Exposure to Ionizing Radiation""
""2.2.1 Radiation Exposures Received by the U.S. Population""""2.2.2 Medical Exposures""; ""2.2.3 Space Radiation Exposures During Previous Space Missions""; ""2.2.4 Radiation Exposures During Jet Aircraft Flights""; ""2.3 Key Issues""; ""3. Biology Pertinent to Variations in Individual Susceptibility with Respect to Radiation Risks for Astronauts""; ""3.1 Overview""; ""3.2 Average Risks for Radiation-Induced Diseases of Concern for Astronauts""; ""3.2.1 Cancer Risk""; ""3.2.2 Heritable Risk""; ""3.2.3 Embryo and Fetal Risk""; ""3.2.4 Other Risks Associated with Radiation Exposure""
""3.3 Evidence of Variation in Radiation Sensitivity and Susceptibility to Effects of Principal Concern""""3.3.1 Evidence of Genetic Variation in Radiation Sensitivity from Cellular and Molecular Research""; ""3.3.2 Evidence for Variation in Radiation Sensitivity from Animal Studies""; ""3.3.3 Evidence of Variation in Radiation Sensitivity from Human Studies""; ""3.3.4 Genetic Sources of Variation in Cancer Susceptibility""; ""3.3.5 Impact of Genetic Variation on Radiation Risk""; ""3.3.6 Congenital Sources of Variation in Cancer Susceptibility""
""3.3.7 Special Considerations for Astronauts""""3.3.8 Key Issues""; ""4. Predicting Cancer Risks from Previous Radiation or Chemotherapy Treatments""; ""4.1 Introduction""; ""4.2 Second Cancers After Radiation Therapy""; ""4.2.1 Carcinogenic Effects of Radiation""; ""4.2.2 Factors Affecting Risk of Second Malignancy""; ""4.3 Risk of Radiation-Induced Malignancies""; ""4.3.1 Radiation-Induced Leukemia""; ""4.3.2 Radiation-Induced Solid Tumors""; ""4.4 Characteristics of Medical Radiation Exposures""; ""4.4.1 Radiation Dose""; ""4.4.2 Radiation Treatment Planning and Delivery""
Bibliography Includes bibliographical references (pages 132-159)
Notes Print version record
Subject Radiation Injuries -- etiology.
Astronauts.
Environmental Exposure -- adverse effects.
Genetic Predisposition to Disease.
Risk Assessment.
Space Flight.
Astronauts -- Health risk assessment.
Radiation injuries -- Genetic aspects.
Space flight -- Health aspects.
Form Electronic book
Author National Council on Radiation Protection and Measurements.
ISBN 1441693904 (electronic bk.)
1613440553 (electronic bk.)
9781441693907 (electronic bk.)
9781613440551 (electronic bk.)