| Description |
1 online resource (xiii, 286 pages) : illustrations (some color) |
| Contents |
1. PREFACE -- 2. The history of the Myelodysplastic Syndromes -- 3. Susceptibility to MDS: DNA repair and detoxification genes -- 4. Myelodysplastic syndromes/neoplasms: Morphological and Immunohistochemical features and standard evaluation -- 5. Diagnostic Criteria and Classification of Myelodysplastic Syndromes -- 6. Cytogenetics of MDS -- 7. Molecular changes in myelodysplastic syndrome -- 8. Prognostic Scoring in MDS -- 9. Flow Cytometry in Myelodysplastic Syndromes -- 10. MDS as an Autoimmune Process -- 11. The Myelodysplastic Overlap Syndromes -- 12. Iron and copper Metabolismin the Myelodysplastic Syndromes -- 13. Pathogenesis and Management of Iron Overload in MDS -- 14. Cytokines in MDS. Abnormalities and treatment -- 15. Therapeutic Modalities and new molecular targets in MDS -- 16. Haematopoietic Stem Cell Transplantation in MDS for Adults -- 17. JMML and Myelodysplastic Syndrome in children |
| Summary |
Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients' symptomatic cytopenias. MDS was previously named as ""preleukemia "" or "" smoldering leukemia"" as the lack of terminal cells in MDS and because about 25% of all cases progresses into acute myeloid leukemia. According to various reports the annual incidence of MDS ranges widely from 2-12 per 100.000, increasing to 30-50 cases per 100.000 among persons aged 70 or older. It is believed that the true incidence of MDS have been underestimat |
| Analysis |
hematologie |
|
haematology |
|
geneeskunde |
|
medicine |
|
volksgezondheid |
|
public health |
|
biomedische wetenschappen |
|
biomedicine |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer eBooks |
| Subject |
Myelodysplastic syndromes.
|
|
Myelodysplastic Syndromes
|
|
medicines (material)
|
|
MEDICAL -- Endocrinology & Metabolism.
|
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Myelodysplastic syndromes
|
| Form |
Electronic book
|
| Author |
Várkonyi, Judit
|
| LC no. |
2011921323 |
| ISBN |
9789400704404 |
|
9400704402 |
|
9789400704398 |
|
9400704399 |
|
