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Book Cover
E-book
Author Bountra, Chas

Title Pain : Current Understanding, Emerging Therapies, and Novel Approaches to Drug Discovery
Published Hoboken : CRC Press, 2003

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Description 1 online resource (1006 pages)
Contents Front Cover; Title Page; Preface; Contents; Chapter 1- Mechanism-Based Classifications of Painand Analgesic Drug Discovery; Chapter 2- Sites of Analgesic Action; Chapter 3- From Acute to Chronic Pain Peripheral and Central Mechanisms; Chapter 4- Central and Peripheral Components of Neuropathic Pain; Chapter 5- A New Perspective on Signal Transduction in Neuropathic Pain; Chapter 6- Pain and the Somatosensory Cortex; Chapter 7- Descending Pathways in Spinal Cord Stimulation and Pain Control; Chapter 8- Local Neuroimmune Interactions in Visceral Hyperalgesia
Chapter 9- Pain Processing in the PeripheryChapter 10- Neuroimaging of Pain; Chapter 11- Surrogate Models of Pain; Chapter 12- Acute Trauma and Postoperative Pain; Chapter 13- Effectiveness of Needling Techniques with Special Reference to Myofascial Pain Syndromes; Chapter 14- Advances in the Management of Spinal Pain and Radiofrequency Techniques; Chapter 15- Pulsed Radiofrequency Treatment of Chronic Neck, Back, Sympathetic, and Peripheral Neuroma-Derived Pain; Chapter 16- Spinal Cord Stimulation; Chapter 17- Spinal Endoscopy; Chapter 18- Cancer Pain Treatment
Chapter 19- Inflammatory Joint Disease and PainChapter 20- Chronic Nonmalignant Visceral Pain Syndromes of the Abdomen, Pelvis, and Bladder and Chronic Urogenital and Rectal Pain; Chapter 21- Nerve Injury Pain; Chapter 22- Sympathetically Maintained Pain; Chapter 23- Headache; Chapter 24- Psychological Factors in Measurement of Pain; Chapter 25- Challenges and Pitfalls of Clinical Trials; Chapter 26- Molecular Approaches to the Study of Pain; Chapter 27- Molecular Validation of Pain Targets; Chapter 28- Genetics of Pain; Chapter 29- Animal Models of Pain
Chapter 30- An Overview of Current and Investigational Drugs for the Treatmentof Acute and Chronic PainChapter 31- Novel Mu, Delta, and Kappa Agonists; Chapter 32- Delta-Receptor, Nonpeptide Agonists; Chapter 33- Peripheral Opioid Analgesia; Chapter 34- Profile of ADL 2-1294, an Opioid Antihyperalgesic Agent with Selectivity for Peripheral Mu-Opiate Receptors; Chapter 35- Controlled-Release Opioids; Chapter 36- NMDA-Receptor Antagonists as Enhancers of Analgesic Activity; Chapter 37- CCK Antagonist Potentiation of Opioid Analgesia; Chapter 38- Profile of NSAID + Opioid Combination Analgesics
Chapter 39- NSAIDs and COX-2 InhibitorsChapter 40- COX-2-Specific Inhibitors; Chapter 41- NK Receptor Antagonists; Chapter 42- Vanilloids; Chapter 43- The Development of Bradykinin Antagonistsas Therapeutic Agents; Chapter 44- The Treatment of Neuropathic Pain; Chapter 45- N-Methyl-D-Aspartate (NMDA) Receptors as a Target for Pain Therapy; Chapter- Profile of Ketamine, CPP, Dextromethorphan, and Memantine; Chapter 47- GV 196771 A, a New Glycine Site Antagonist of the NMDA Receptor with Potent Antihyperalgesic Activity; Chapter 48- Voltage-Gated Sodium Channels and Pain
Summary This reference presents a detailed overview of approaches and techniques in the management of pain caused by tissue, nerve and central nervous system injuries, categorizing pain into a variety of syndromes and underlying mechanisms to aid the development of interventional pharmacologic measures
Notes Chapter 49- Calcium Channel Antagonists and the Control of Pain
Print version record
Subject Pain -- Chemotherapy
Pain -- Treatment.
Pain -- Chemotherapy
Pain -- Treatment
Form Electronic book
Author Munglani, Rajesh
Schmidt, William K
ISBN 9781135532512
1135532516