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Book Cover
E-book
Author Hao, Da Cheng, author

Title Ranunculales medicinal plants : biodiversity, chemodiversity and pharmacotherapy / Da-Cheng Hao
Published London : Academic Press, [2018]
©2018
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Description 1 online resource : illustrations
Contents Intro; Title page; Table of Contents; Copyright; About the Author; Preface; Chapter 1: Genomics and Evolution of Medicinal Plants; Abstract; 1.1. Introduction; 1.2. Evolution of Genome, Gene, and Genotype; 1.3. Mechanisms of Species Evolution and Diversification; 1.4. Phenotype Evolution and Ecology; 1.5. Pharmacophylogeny vs. Pharmacophylogenomics; 1.6. Conclusion and Prospects; Chapter 2: Mining Chemodiversity From Biodiversity: Pharmacophylogeny of Ranunculaceae Medicinal Plants; Abstract; 2.1. Introduction; 2.2. Systematics of Ranunculaceae
2.3. The Chemical Composition of Ranunculoideae Plants2.4. The Chemical Composition of Thalictroideae, Coptidoideae, Hydrastidoideae, and Glaucidioideae; 2.5. Ethnopharmacology and Bioactivity; 2.6. Discussion; 2.7. Conclusion; Chapter 3: Mining Chemodiversity From Biodiversity: Pharmacophylogeny of Ranunculales Medicinal Plants (Except Ranunculaceae); Abstract; 3.1. Introduction; 3.2. Systematics and Evolution of Ranunculales; 3.3. The Chemical Composition of Berberidaceae Plants; 3.4. The Chemical Composition of Menispermaceae
3.5. The Chemical Composition of Lardizabalaceae and Circaeasteraceae Plants3.6. The Chemical Composition of Papaveraceae and Eupteleaceae Plants; 3.7. Ethnopharmacology and Bioactivity; 3.8. Discussion and Conclusion; Chapter 4: Drug Metabolism and Pharmacokinetic Diversity of Ranunculaceae Medicinal Compounds; Abstract; Abbreviations; 4.1. Introduction; 4.2. Absorption of Ranunculaceae Compounds; 4.3. Distribution; 4.4. Metabolism; 4.5. Toxicity; 4.6. Pharmacokinetics and Pharmacodynamics; 4.7. Conclusion and Prospect
6.6. Immunomodulatory Activity6.7. Antiinflammatory Activity; 6.8. Structure-Activity Relationship; 6.9. Genomics, Transcriptomics, Proteomics, and Metabolomics; 6.10. Conclusion and Future Perspective; Chapter 7: Biodiversity, Chemodiversity, and Pharmacotherapy of Thalictrum Medicinal Plants; Abstract; 7.1. Introduction; 7.2. Chemical Constituents; 7.3. Bioactivity; 7.4. Phylogeny; 7.5. Discussion and Conclusion; Chapter 8: Biodiversity, Chemodiversity, and Pharmacotherapy of Anemone Medicinal Plants; Abstract; Abbreviations; 8.1. Introduction; 8.2. Ethnopharmacology
Chapter 5: Drug Metabolism and Disposition Diversity of Ranunculales PhytometabolitesAbstract; Abbreviations; 5.1. Introduction; 5.2. Absorption; 5.3. Distribution; 5.4. Metabolism; 5.5. Excretion and Elimination; 5.6. Toxicity and Safety; 5.7. Pharmacokinetics and Pharmacodynamics; 5.8. Conclusions and Prospect; Chapter 6: Anticancer Chemodiversity of Ranunculaceae Medicinal Plants; Abstract; Abbreviations; 6.1. Introduction; 6.2. Cell Death Pathways; 6.3. MicroRNAs, DNA Damage, and Epigenetic Regulation; 6.4. Oxidative Process and Metabolism; 6.5. Antiangiogenic and Antimetastatic Effects
Summary Ranunculales is an order of flowering plants belonging to a paraphyletic group known as the basal eudicots. Medicinal plants of this order provide myriad pharmaceutically active components commonly used worldwide in ethnomedicine and traditional Chinese medicine. Interest in plant-based medicinal resources has led to discoveries of many novel compounds in various species, and to investigations on their chemodiversity, biodiversity and pharmacotherapy. Ranunculales Medicinal Plants covers this order of flowering plants comprehensively in this context; detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera, and their relevance to drug efficacy. The book carries out an exhaustive survey of the literature in order to characterize global trends in the application of flexible technologies. The interrelationship between Chinese species and between Chinese and non-Chinese species is inferred, in the text, through molecular phylogeny, based on nuclear and chloroplast DNA sequencing. The title discusses the conflict between chemotaxonomy and molecular phylogeny, in the context of drug discovery and development. It offers invaluable and holistic coverage for the study of Ranunculales as a pharmaceutical resource
Bibliography Includes bibliographical references and index
Notes Vendor-supplied metadata
Subject Herbal Medicine
Plants, Medicinal
Berberidaceae -- chemistry
Berberidaceae -- drug effects
Menispermaceae -- chemistry
Menispermaceae -- drug effects
Papaveraceae -- chemistry
Papaveraceae -- drug effects
Ranunculaceae -- chemistry
Ranunculaceae -- drug effects
Ranunculales
NATURE -- Plants -- General.
Ranunculales.
Form Electronic book
ISBN 0128142332 (electronic bk.)
9780128142332 (electronic bk.)