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Book Cover
Author Yamaguchi, T. (Takami), 1948- author

Title Integrated Nano-Biomechanics / Takami Yamaguchi, Takuji Ishikawa, Yohsuke Imai
Published Amsterdam, Netherlands : Elsevier, [2018]
Online access available from:
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Description 1 online resource
Series Micro & nano technologies series
Micro & nano technologies
Contents Front Cover; Integrated Nano-Biomechanics; Copyright; Contents; Contributors; Preface; Chapter 1: Introduction; Chapter 2: Biomechanics of Microcirculation; 2.1. Behavior Of Capsules In Flow; 2.1.1. Governing Equations and Numerical Method; 2.1.2. Capsules in an Unbounded Simple Shear Flow; 2.1.3. Lateral Migration of Capsules in Shear Flow; 2.1.4. Capsules in an Oscillatory Shear Flow; 2.2. Behavior Of Red Blood Cells; 2.2.1. Mechanical Modeling of RBCs; 2.2.2. An RBC in Simple Shear Flow; Tumbling-Swinging Transition; 2.2.3. An RBC Flowing Thorough a Micropore
2.3. Cell Adhesion In Microvessels2.3.1. Margination in Microvessels; 2.3.2. Cell Adhesion in Capillaries; 2.3.3. Malaria Infection; 2.4. Formation And Destruction Of The Primary Thrombus; 2.4.1. Physiology and Pathology of Primary Thrombus in Blood Flow; 2.4.2. Particle Method Simulation; 2.4.3. Simulation of Primary Thrombus Formation and Influence of Vessel Geometry; 2.4.4. Influence of Platelet Glycoprotein Receptors and SIPA; 2.4.5. Interaction Between Platelets and RBCs on the Primary Thrombus Formation and Mechanical Hemolysis; 2.4.6. Summary; References
4.1. Development of Cerebral Aneurysms4.1.1. Anatomically Realistic Artery Model; 4.1.2. Blood Flow Simulation; 4.1.3. Gradient Oscillatory Number (GON); 4.1.4. Summary; 4.2. Electroporation for Cancer Treatment; 4.2.1. Electroporation; 4.2.2. Cell Death Under Electric Fields; 4.2.3. Cellular Signaling: Caspases Activation and Intracellular Calcium; 4.2.4. Inhibition of Apoptosis; 4.2.5. Effect on Cell Growth Under Mild Electric Field; 4.3. Microbubbles for Blood Oxygenation; 4.3.1. Introduction; 4.3.2. Properties and Theory of Microbubble; 4.3.3. Generation of Microbubbles
4.3.4. Oxygen Gas-Solubility and the Effect of Solutes4.3.5. Oxygen Supersaturated Fluid; 4.3.6. Blood Oxygenation; 4.3.7. Summary; References; 4.4. Percutaneous Absorption of Medicine; 4.4.1. Introduction; 4.4.2. Drug Administrations for Clinical Medicines; 4.4.3. Transdermal Drug Delivery (TDD); 4.4.4. Enhancement of TDD; References; Chapter 5: Ciliary Motion; 5.1. Structure of a Cilium; 5.1.1. Cilia and Flagella; 5.1.2. Cilia on Airway, Brain, and Sperm Cells; 5.1.3. Motility of Cilia and Flagella; 5.1.4. Structure of Cilia and Flagella; 5.1.5. Structure of Respiratory Cilia
Chapter 3: Biomechanics of the Digestive System3.1. Dynamics of Swallowing; 3.1.1. Videofluoroscopy and Wall Motion; 3.1.2. CFD Modeling of Swallowing; 3.2. Gastric Motility and Flow in the Stomach; 3.2.1. Antral Recirculation During Gastric Mixing; 3.2.2. Reynolds and Strouhal Numbers; 3.2.3. Terminal Antral Contraction; 3.3. Transport Phenomena of Gut Flora; 3.3.1. Gut Flora; 3.3.2. Momentum Transport in the Intestine; 3.3.3. Mass Transport in the Intestine; 3.3.4. Bacterial Transport in the Intestine; References; Chapter 4: Biomechanics for Pathology and Treatment
Summary "Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production. This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases. Provides knowledge of integrated biomechanics, focusing on nano-scale, in this rapidly growing research field Explains how the different technologies can be integrated and applied in a variety of biomedical application fields, as well as for alternative energy sources Uses a collaborative, multidisciplinary approach to provide a comprehensive coverage of nano-biomechanics"-- Provided by publisher
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (EBSCO, viewed June 29, 2018)
Subject Biomechanics
SCIENCE -- Chemistry -- Industrial & Technical.
TECHNOLOGY & ENGINEERING -- Chemical & Biochemical.
Form Electronic book
Author Imai, Yohsuke, editor
Ishikawa, Takuji, editor
ISBN 0323389597 (electronic bk.)
9780323389594 (electronic bk.)