eclampsia -- Preconceptional and periconceptional pathways to preeclampsia -- Placentation and placental function in normal and preeclamptic pregnancies -- Unbiased approaches for addressing the complexities of the placenta's role in the preeclampsia syndrome -- The immunology of preeclampsia -- Trophoblast extracellular vesicles in preeclampsia -- Angiogenesis and preeclampsia -- Vascular endothelial cell dysfunction in preeclampsia -- Cardiovascular alterations in normal and preeclamptic pregnancy -- Cardiometabolic antecedents of preeclampsia -- Cerebrovascular pathophysiology in preeclampsia and eclampsia -- The kidney in normal pregnancy and preeclampsia -- Salt, aldosterone, and the renin-angiotensin system in pregnancy -- Platelets, coagulation, and the liver -- Clinical management and antihypertensive treatment of hypertensive disorders of pregnancy -- Prediction and prevention of preeclampsia -- Long-term effects of preeclampsia on mothers and offspring -- Animal models used for investigating pathophysiology of preeclampsia and identifying therapeutic targets -- Harmonization of data and biobanks for preeclampsia research

Summary Leon Chesley's Hypertensive Disorders in Pregnancy was initially published in 1978. Four decades later, hypertension complications in pregnancy are still a major cause of fetal and maternal morbidity and death, especially in less developed nations. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this, hypertensive disorders remain marginally studied and management is often controversial. Chesley's Hypertensive Disorders in Pregnancy, Fifth Edition continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. This revision focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. It provides a superb analysis of the multiple topics that relate to hypertension in pregnancy, especially of preeclampsia

Bibliography Includes bibliographical references and indexes

Notes Description based on online resource; title from resource home page (ClinicalKey, viewed February 2, 2022)

Subject Hypertension in pregnancy.

Hypertension, Pregnancy-Induced

Pre-Eclampsia

Hypertension in pregnancy

Form Electronic book

Author Taylor, Robert N., 1953- editor.

Conrad, Kirk P., editor

Davidge, Sandra T., editor

Staff, Anne Cathrine, editor

Roberts, James M., 1941- editor.

ISBN 9780128184189

0128184183

9780128184172

0128184175

9780323763035

0323763030

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