Limit search to available items
9 results found. Sorted by relevance | date | title .
Book Cover
E-book

Title Mitochondrial oxidative phosphorylation : nuclear-encoded genes, enzyme regulation, and pathophysiology / edited by Bernhard Kadenbach
Published New York ; London : Springer, 2012
Online access available from:
Springer eBooks    View Resource Record  

Copies

Description 1 online resource : illustrations (some color)
Series Advances in experimental medicine and biology ; 748
Advances in experimental medicine and biology ; 748
Contents Introduction to Mitochondrial Oxidative Phosphorylation / Bernhard Kadenbach -- Mitochondrial Dynamics: The Intersection of Form and Function / Andrew Ferree and Orian Shirihai -- Biogenesis of Mitochondrial Proteins / Johannes M. Herrmann, Sebastian Longen, Daniel Weckbecker and Matthieu Depuydt -- Assembly Factors of Human Mitochondrial Respiratory Chain Complexes: Physiology and Pathophysiology / Daniele Ghezzi and Massimo Zeviani -- Supramolecular Organisation of the Mitochondrial Respiratory Chain: A New Challenge for the Mechanism and Control of Oxidative Phosphorylation / Giorgio Lenaz and Maria Luisa Genova -- Molecular Mechanisms of Superoxide Production by the Mitochondrial Respiratory Chain / Stefan Dröse and Ulrich Brandt -- Studies on the Function and Regulation of Mitochondrial Uncoupling Proteins / Richard K. Porter -- Evolution of the Couple Cytochrome c and Cytochrome c Oxidase in Primates / Denis Pierron, Derek E. Wildman, Maik Hüttemann, Thierry Letellier and Lawrence I. Grossman -- Reaction Mechanism of Mammalian Mitochondrial Cytochrome c Oxidase / Shinya Yoshikawa, Kazumasa Muramoto and Kyoko Shinzawa-Itoh -- Phosphorylation of Mammalian Cytochrome c and Cytochrome c Oxidase in the Regulation of Cell Destiny: Respiration, Apoptosis, and Human Disease / Maik Hüttemann, Icksoo Lee, Lawrence I. Grossman, Jeffrey W. Doan and Thomas H. Sanderson -- Individual Biochemical Behaviour Versus Biological Robustness: Spotlight on the Regulation of Cytochrome c Oxidase / Rabia Ramzan, Petra Weber, Bernhard Kadenbach and Sebastian Vogt -- Bigenomic Regulation of Cytochrome c Oxidase in Neurons and the Tight Coupling Between Neuronal Activity and Energy Metabolism / Margaret T.T. Wong-Riley -- Cytochrome c Oxidase and Its Role in Neurodegeneration and Neuroprotection / Susanne Arnold -- The Many Clinical Faces of Cytochrome c Oxidase Deficiency / Salvatore DiMauro, Kurenai Tanji and Eric A. Schon
Summary This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea. The main function of mitochondria, the synthesis of ATP, is performed at subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a regulatory function. However, the specific physiological functions of the nuclear encoded subunits of complexes I, III, IV, and V are mostly unknown. New data indicates that they are essential for life of higher organisms, which is characterized by an adult life without cell division (postmeiotic stage) in most tissues, after the juvenile growth. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms. Defective genes of some subunits were shown to induce mitochondrial diseases. Mitochondrial genes and human diseases will also be covered
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Mitochondrial DNA.
Mitochondrial pathology.
Eukaryotic cells.
Cytochrome c Group.
Subcellular Fractions.
Multienzyme Complexes.
Phosphorylation.
Metabolism.
Energy Metabolism.
Organelles.
Phenomena and Processes
Cytoplasmic Structures.
Biochemical Phenomena.
Cytochromes.
Cellular Structures.
Enzymes.
Chemical Phenomena.
Hemeproteins.
Enzymes and Coenzymes.
Cytoplasm.
Cells.
Proteins.
Chemicals and Drugs
Intracellular Space.
Anatomy.
Amino Acids, Peptides, and Proteins.
Oxidative Phosphorylation.
Electron Transport Chain Complex Proteins.
Mitochondria.
Cytochromes c
Form Electronic book
Author Kadenbach, Bernhard, 1933-
LC no. 2012938858
ISBN 9781461435730 (electronic bk.)
1461435730 (electronic bk.)
1493901567
9781493901562