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Book Cover
Author Stewart, W. B.

Title World Cancer Report 2014
Published Geneva : IARC, 2014
Online access available from:
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Description 1 online resource (1097 pages)
Contents Front Cover -- Title Page -- Copyright Page -- World Cancer Report 2014 -- Contributors -- Contents -- Foreword -- Preface -- Introduction -- Perspectives -- Elizabeth H. Blackburn -- Reconciling stress and cancer: insights from telomeres -- Cesar G. Victora -- Early-life exposures, birth cohorts, and noncommunicable diseases (with special reference to cancer) -- Harald zur Hausen -- Prenatal infections with subsequent immune tolerance could explain the epidemiology of common childhood cancers -- Mel Greaves -- An evolutionary foundation for cancer control -- Walter C. Willett -- Diet, nutrition, and cancer: where next for public health? -- Barnett S. Kramer -- Controversies in cancer screening and their resolution: a view from the United States "battleground" -- Richard Peto -- The full hazards of smoking and the benefits of stopping: cancer mortality and overall mortality -- 1 Cancer worldwide -- 1.1 The global and regional burden of cancer -- 1.2 Transitions in human development and the global cancer burden -- 1.3 Childhood cancer -- 2 Cancer etiology -- 2.1 The global tobacco epidemic -- 2.2 Tobacco smoking and smokeless tobacco use -- Genetic susceptibility to tobacco-related cancers -- 2.3 Alcohol consumption -- 2.4 Infections -- Inflammation and cancer -- Do infections play a role in breast cancer? -- 2.5 Reproductive and hormonal factors -- 2.6 Diet, obesity, and physical activity -- Challenges of measuring diet in cancer epidemiological studies and new perspectives -- Single-nucleotide polymorphisms relevant to meat consumption and cancer risk -- Diet and the gut microbiome -- 2.7 Occupation -- Evaluating carcinogens: dioxins and dioxin-like substances -- Preventing occupational cancer: successes and failures -- 2.8 Radiation: ionizing, ultraviolet, and electromagnetic -- An IARC announcement that made waves
2.9 Pollution of air, water, and soil -- Bisphenol A and cancer -- Pesticides and cancer -- 2.10 Pharmaceutical drugs -- Breast implants and cancer -- 2.11 Naturally occurring chemical carcinogens -- 3 Cancer biology -- 3.1 Genomics -- TP53 mutations and human cancer -- 3.2 Genome-wide association studies -- Gene-environment interactions and breast cancer DNA repair polymorphisms and human cancer -- 3.3 Gene expression -- Therapeutic implications of dysregulated DNA damage signalling -- 3.4 Epigenetics -- The non-coding RNA revolution in medical research -- Causes and consequences of microRNA dysregulation in cancer -- 3.5 Metabolic change and metabolomics -- 3.6 Stem cells and cancer stem cells -- Stem cells in cancer: determinants of clinical outcome? -- 3.7 Tumour microenvironment -- 3.8 Signal transduction and targeted therapy -- 3.9 Immunology and immunotherapy -- Role of the innate and acquired immune systems in mammary development and breast cancer -- Premortem autophagy and endoplasmic reticulum stress as immunogenic signals in cancer therapy -- 4 Cancer prevention -- 4.1 Changing behaviours -- tobacco control -- Australia's plain packaging of tobacco products -- Tobacco and China -- 4.2 Changing behaviours -- physical activity and weight control -- Energy restriction, age, and cancer risk -- EPIC as a model study vehicle -- 4.3 Designing and evaluating population-wide campaigns -- 4.4 Prevention strategies common to noncommunicable diseases -- The global economics of chronic and noncommunicable diseases -- 4.5 Legislative and regulatory initiatives -- Environmental pollution: old and new -- Taxing sugar-sweetened beverages: the Brazilian case -- 4.6 Vaccination -- Early implementation and monitoring of HPV vaccination in Bhutan -- Introduction and monitoring of a national HPV vaccination programme in Rwanda -- 4.7 Screening -- principles
4.8 Screening -- implementation -- 5 Cancer by organ site -- A guide to the epidemiology data in World Cancer Report -- 5.1 Lung cancer -- Earliest molecular evidence of tobacco-induced injury in the airway -- Biomarkers of air pollution -- 5.2 Breast cancer -- Biological mechanisms mediating reduced breast cancer risk through physical activity -- Treatment determined by BRCA1/2 mutation -- 5.3 Oesophageal cancer -- Risk of malignant progression in Barrett oesophagus patients -- 5.4 Stomach cancer -- Gastric cancer prevention -- 5.5 Colorectal cancer -- Lgr5 stem cells in self-renewal and intestinal cancer -- Tumour-elicited inflammation and malignant progression in colorectal cancer -- 5.6 Liver cancer -- Treating chronic hepatitis with antiviral drugs to prevent liver cancer -- 5.7 Pancreatic cancer -- 5.8 Head and neck cancers -- 5.9 Kidney cancer -- 5.10 Bladder cancer -- 5.11 Cancers of the male reproductive organs -- 5.12 Cancers of the female reproductive organs -- 5.13 Haematopoietic and lymphoid malignancies -- Molecular detection of minimal residual disease in childhood leukaemia -- De novo DNA methyltransferases in normal and malignant haematopoiesis -- 5.14 Skin cancer -- Evaluating sunscreen as a measure to reduce the risk of melanoma -- 5.15 Thyroid cancer -- 5.16 Tumours of the nervous system -- Glioma genomics and its implications in neuro-oncology -- 6 Cancer control -- 6.1 National cancer control plans -- 6.2 Current global national cancer control capacity -- Cervical cancer prevention in six African countries -- Traditional household cooking: risks and prevention -- 6.3 Health systems strengthening for cancer control -- Towards understanding the economics of cancer: priority areas for research -- 6.4 Research infrastructure -- biobanks, cohorts, registries, and data linkage -- 6.5 Advocacy for cancer control
6.6 Law in cancer control -- 6.7 The global economic burden of cancer -- Cancer control experiences -- Cancer control in Africa: options for a vulnerable continent -- Cancer control in Canada: challenges and strategies in a high-income country -- Cancer control in China: preventive policies and accessible health care -- Cancer control in France: towards patient-centred precision medicine -- Cancer control in India: cancer care through a four-tier system -- Cancer control in Jordan: goals for low- and middle-income countries -- Cancer control in Morocco: action in harmony with the socioeconomic and cultural context -- Cancer control in Peru: "El Plan Esperanza" -- the Hope Plan -- Cancer control in Turkey: an encouraging national cancer control plan for the future -- Contributors -- Disclosures of interests -- Sources -- Back Cover
Summary Biology . Cancer Prevention . Cancer by Organ Site . Cancer Control Also available: Online version (EPUB): World Cancer Report 2014 Online (EPUB) version EPUB - is an open e-book standard. It provides reflowable content meaning that the text adapts to fit the screen of various devices including iPad iPhone iPod Touch Kobo eReader Nook and the Sony Reader
This book from the International Agency for Research on Cancer the specialized cancer agency of the World Health Organization provides a unique global view of cancer including cancer patterns causes and prevention. The World Cancer Report series is recognized as an authoritative source of global perspective and information on cancer. The first volume appeared in 2003 and the second in 2008. This third volume in the series encompasses both established knowledge and recent research achievement. World Cancer Report provides a professional multidisciplinary assessment of all aspects of the geographical distribution biology etiology prevention and control of cancer predicated on research. The concise nature of the text and the high graphic content (hundreds of colour maps diagrams and photographs) make the publication accessible to a broad readership. World Cancer Report is designed to provide non-specialist health professionals and policy-makers with a balanced understanding of cancer control and to provide established cancer professionals with insights about recent development. The book includes chapters in which distinguished scientists from around the world provide a broad overview of established knowledge and then emphasize research activity and progress. In addition text boxes distributed throughout the book provide short in-depth discussions of selected questions or topics. A new feature of this volume is the inclusion of Perspectives considering the future development of different aspects of cancer research written by those whose record of outstanding achievement qualifies them as individuals having unique vision. Includes more than 60 chapters with contributions from more than 150 distinguished scientists from around the world with information on: . Cancer Worldwide . Cancer Etiology . Cancer
Subject Cancer -- Epidemiology.
Cancer -- Etiology.
Cancer -- Prevention.
World health.
Form Electronic book
Author International Agency for Research on Cancer.
Wild P.C.
ISBN 9283204298
9789283204343 (electronic bk.)