Limit search to available items
Book Cover
E-book

Title Structural virology / Mavis Agbandje-McKenna [and others], editors
Published Cambridge : Royal Society of Chemistry, [2010], ©2011

Copies

Description 1 online resource (299 pages)
Series RSC Biomolecular Sciences ; 21
RSC biomolecular sciences ; 21.
Contents Introduction: Principles of Virus Structure Section 1Methodologies for Structural Analysis of Viruses Production and Purification of Viruses for Structural Studies Microscopic (Confocal) Analysis of Viral Entry and Infection Cryo-electron Microscopy of Virus Infection -- Tomography and Asymmetric Structure Determination Cryo-electron Microscopy of Viruses -- 3D of Virus Capsids X-ray Crystallography of Virus Capsids Structural Studies of Viral Proteins Probing Viral Capsid Structures in Solution Section 2Structure to Function Correlation for Viruses Evolution of Viral Capsid Structures -- the Three Domains of Life Mechanisms of Virus Capsid Assembly Mechanisms of Genome Packaging Attachment and Viral entry -- Receptor Recognition in Viral Pathogenesis Attachment and Entry -- Viral Cell Fusion Virus Antibody Recognition Section 3Therapeutic Strategies Based on Viral Structures Development of anti-HIV drugs Design of Influenza Vaccines and Antiviral Agents Engineering Viral Capsids as Nano Tools Viral Vectors for Gene Delivery
Summary Over the last ten years, much effort has been devoted to improving the biophysical techniques used in the study of viruses. This has resulted in the visualization of these large macromolecular assemblages at atomic level, thus providing the platform for functional interpretation and therapeutic design. Structural Virology covers a wide range of topics and is split into three sections. The first discusses the vast biophysical methodologies used in structural virology, including sample production and purification, confocal microscopy, mass spectrometry, negative-stain and cryo-electron microscop
Notes Online resource; title from title screen (viewed on June 15, 2010)
Subject Viruses -- Morphology.
Molecular virology.
Viral proteins.
Proteins.
Viruses.
Organisms
Viral Structural Proteins
Microbiological Phenomena
Phenomena and Processes
Viral Proteins
Proteins
Amino Acids, Peptides, and Proteins
Chemicals and Drugs
Nucleocapsid Proteins
Viruses
Virus Physiological Phenomena
protein.
Chemistry.
Molecular biology.
SCIENCE -- Life Sciences -- Biology.
SCIENCE -- Life Sciences -- Microbiology.
Viruses
Viral proteins
Proteins
Molecular virology
Viruses -- Morphology
Form Electronic book
Author Agbandje-McKenna, Mavis
ISBN 9781849732239
184973223X