Cover ; Title Page ; Copyright ; Contents ; Contributors ; Preface ; Foreword ; Chapter 1 The Burden of Healthcare-Associated Infection ; Key Messages ; What We Know -- The Evidence ; What We Do Not Know -- The Uncertain ; Research Agenda ; References
Chapter 2 Historical Perspectives References; Chapter 3 Flora and Physiology of Normal Skin ; Key Messages ; Research Agenda ; References ; Chapter 4 Dynamics of Hand Transmission ; Key Messages ; What We Know -- The Evidence ; Organisms Present on Patients' Skin or Immediate Environment
Organism Transfer to Healthcare Workers' Hands Organism Survival on Hands ; Defective Hand Cleansing Results in Hands Remaining Contaminated ; Contaminated Hands Cross-Transmit Organisms ; Impact of Hand Hygiene on Transmission ; What We Do Not Know -- The Uncertain ; Research Agenda
Methodological challenges and Recommendations Recommendation 1: Studies Should Clearly State the Intended Causal Contrast ; Recommendation 2: Confounding and Contamination Should Be Considered in Hand Hygiene Studies but Generally Do Not ""Explain"" a Positive Result
Bibliography
References Chapter 5 Mathematical Models of Handborne Transmission of Nosocomial Pathogens ; Key Messages ; What We Know-The Evidence ; What We Do Not Know-The Uncertain ; Research Agenda ; References ; Chapter 6 Methodological Issues in Hand Hygiene Science ; Key Messages
Notes
Recommendation 3: Hand Hygiene Studies Should Characterize Their Target Populations of Healthcare Workers and Should Attempt to More Fully Address Heterogeneity of Compliance
