| Description |
1 online resource |
| Contents |
Cover -- Half Title -- Title Page -- Copyright Page -- Preface -- Contents -- Detailed Contents -- Chapter 1: Statistical Thermodynamics of Biological Molecules -- 1.1 BIOLOGICAL MOLECULES HAVE SPECIAL CHEMICAL PROPERTIES -- Water Shapes the Properties of All Biological Structures -- The Structures of Biological Macromolecules are Key to their Function -- The Structures of Proteins that Exist Today have been Selected by Evolution -- Interactions in Biomolecules are Weak -- Communication Occurs through Interactions between Molecules or within Molecules |
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1.2 STATISTICAL THERMODYNAMICS RELATES MICROSCOPIC INTERACTIONS TO MACROSCOPIC PROPERTIES -- States with the Same Energy are Equally Probable -- States with Lower Energies have a Higher Probability -- 1.3 THE ENERGY OF AN ISOLATED SYSTEM IS CONSTANT -- THE ENTROPY INCREASES TOWARD A MAXIMUM -- The Energy is a Measure of Motion and Interactions in a System -- The Entropy is a Measure of the Number of States -- The Entropy can be Explicitly Related to Probabilities -- The Second Law is a Statement about Probability -- 1.4 THE GIBBS ENERGY IS A MINIMUM AT EQUILIBRIUM |
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The Enthalpy is a Thermodynamic Function More Useful than the Energy in the Laboratory -- The Partition Function is Related to the Gibbs Energy -- The Gibbs Energy Provides the Criterion for Equilibrium at Constant T and P -- 1.5 THE GIBBS ENERGY DETERMINES THE CONCENTRATIONS AT EQUILIBRIUM -- The Chemical Potential of a Component is its Contribution to the Gibbs Energy of the System -- The Chemical Potential Increases with Concentration -- The Standard State must be Clearly Defined -- The Equilibrium Constant Provides a Measurement of the Standard Gibbs Energy Change |
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Equilibrium Constants are Often Reported with Units (as a Reminder of the Standard State) -- 1.6 THE PARTITION FUNCTION IS A POWERFUL TOOL TO STUDY DISTRIBUTIONS OF MOLECULES -- Small Proteins are either Folded or Unfolded -- The Probabilities of Each State can be Obtained from the Partition Function -- 1.7 TWO-STATE SYSTEMS ARE COMMON IN CHEMISTRY -- Ribonuclease A is Almost Entirely Folded at Room Temperature -- The cis and trans Isomers of 2-butene are Populated to Different Extents at Equilibrium -- Nuclear Spins in a Magnetic Field have Almost Identical Populations |
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The Partition Function Gives the Number of Occupied States -- 1.8 SUMMARY -- 1.9 PROBLEMS -- 1.10 FURTHER READING -- Chapter 2: Protein Structure -- 2.1 PROTEINS ARE POLYMERS OF A SPECIAL KIND -- Polypeptides are Formed by Amino Acids Connected by Peptide Bonds -- The Primary Structure of Proteins is the Sequence of Amino Acids -- Amino Acids are the Building Blocks of Proteins -- There are Twenty Amino Acids in Proteins -- 2.2 FLUORESCENCE SPECTROSCOPY IS A USEFUL TECHNIQUE TO MONITOR PROTEIN STRUCTURE AND INTERACTIONS |
| Form |
Electronic book
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| ISBN |
9780429258817 |
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042925881X |
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